All Stories

  1. Peptides from Animal Venoms: A Promising Frontier in Diabetes Therapy via Multi-Target Mechanisms
  2. Yellow mealworm beetle (Tenebrio molitor) larvae as an alternative model for antileishmanial drug evaluation
  3. Functional Studies and Molecular Dynamics Reveal BPP-BrachyNH2-Induced Relaxation in Male Rat Small Mesenteric Arteries via Binding to Argininosuccinate Synthase
  4. Toxicological safety, antioxidant effect, and chemoprotection determination of an extract from the babassu mesocarp ( Orbignya phalerata Mart.) in preclinical studies
  5. Experimental Models of Type 2 Diabetes Mellitus Induced by Combining Hyperlipidemic Diet (HFD) and Streptozotocin Administration in Rats: An Integrative Review
  6. COPRODUTOS DO FRUTO DO BACURIZEIRO (Platonia insignis Mart.) NO CONTROLE GLICÊMICO E INFECÇÕES RESPIRATÓRIAS ASSOCIADAS AO DIABETES TIPO 1
  7. Ciências Farmacêuticas - Edição V
  8. PEPTÍDEOS BIOATIVOS DE VENENOS E SECREÇÕES ANIMAIS: UMA REVISÃO DE SEUS EFEITOS SOBRE O DIABETES MELLITUS TIPO 2
  9. Novel tryptophyllin peptides from Physalaemus centralis inhibit oxidative stress-induced endothelial dysfunction in rat aorta preparation
  10. Mimosa caesalpiniifolia Benth., a Brazilian Caatinga Species with Anti-Hypertensive Properties
  11. Extraction and Identification of Flavonoids from the Leaves of Pilocarpus microphyllus: Focus on Antioxidant Activity and Neuroprotective Profile
  12. MODELOS EXPERIMENTAIS DE DIABETES MELLITUS TIPO 2 EM ROEDORES: MÉTODOS DE INDUÇÃO E APLICAÇÕES
  13. The anxiolytic-like effect of the alkaloid fraction of the psychedelic plant Mimosa tenuiflora (Willd.) Poir
  14. MARCADORES DE FUNÇÃO HEPÁTICA, ATIVIDADE ANTIOXIDANTE E PEROXIDAÇÃO LIPÍDICA EM RATOS SUBMETIDOS A ADMINISTRAÇÃO COMBINADA DE ÁLCOOL ETÍLICO E BEBIDA ENERGÉTICA
  15. Essential Oils: Chemistry and Pharmacological Activities—Part II
  16. Anticorrosive properties in 1020 steel of an alkaloid-rich extract obtained from the jaborandi biomass (Pilocarpus microphyllus staff ex wardlew) of the pilocarpine industrial production chain
  17. AVALIAÇÃO TOXICOLÓGICA AGUDA E ANTI-INFLAMATÓRIA DE Sida santaremnensis H. Monteiro (Malvaceae)
  18. Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings
  19. Toxicity and Teratogenic Potential of Piplartine from Piper tuberculatum Jacq. during Embryonic Development in Mice (Mus musculus)
  20. ANTI-INFLAMMATORY EFFECT OF Anadenanthera colubrina var. cebil (Griseb.) Altschul IN EXPERIMENTAL ELASTASE-INDUCED PULMONARY EMPHYSEMA IN RATS
  21. Beneficial Properties and Sustainable Use of a Traditional Medicinal Plant: Griffonia simplicifolia
  22. Structural Characterization and Rat Aortic Vascular Reactivity of Bradykinin-Potentiating Peptides (BPPs) from the Snake Venom of Bothrops moojeni from Delta do Parnaíba Region, Brazil
  23. Evaluation of the acute toxicity of ellagic acid and gallic acid incorporated in Poloxamer407® gel, in Zophobas morio larvae
  24. Antiviral Action against SARS-CoV-2 of a Synthetic Peptide Based on a Novel Defensin Present in the Transcriptome of the Fire Salamander (Salamandra salamandra)
  25. A Preliminary Study on Hepatoprotective, Hypolipidemic and Aortic Morphometric Effects of Omega-3-Rich Fish Oil in Hypercholesterolemic Mice
  26. ADMET study and inhibition of Staphylococcus aureus efflux pumps by a synthetic p-aminochalcone
  27. Anti-Inflammatory Effect of Anadenanthera Colubrina VAR. Cebil (Griseb.) Altschul in Experimental Elastase-Induced Pulmonary Emphysema in Rats
  28. Effect of chronic apple consumption (Malus domestica Borkh.) on the lipid profile of adults with dyslipidemia: a systematic review
  29. Modulatory Effect of Croton heliotropiifolius Kunth Ethanolic Extract on Norfloxacin Resistance in Staphylococcus aureus
  30. Use of Monoterpenes as Potential Therapeutics in Diabetes Mellitus: A Prospective Review
  31. AVALIAÇÃO TOXICOLÓGICA IN VITRO E IN VIVO DE UM EXTRATO PADRONIZADO OBTIDO DAS INFLORESCÊNCIAS DE Mimosa caesalpiniifolia BENTH
  32. EFEITOS DO (–)-CARVEOL NO ESTRESSE OXIDATIVO E REATIVIDADE VASCULAR EX VIVO EM ARTÉRIA AORTA DE RATOS DIABÉTICOS
  33. EFEITOS DO R-(+)-LIMONENO NO PERFIL GLICÊMICO E ESTRESSE OXIDATIVO EM MODELO EXPERIMENTAL DE DIABETES
  34. Relationship among Dietary Intake of Vitamin E, Lipid Peroxidation Markers, and C-Reactive Protein in Flu-Like Patients Diagnosed with COVID-19
  35. Involvement of the serotoninergic system in the anxiolytic action mechanism of a liposomal formulation containing nimodipine (NMD-Lipo)
  36. ESTUDO DOS EFEITOS DO R-(+)-LIMONENO SOBRE MODELO DE ESTRESSE OXIDATIVO E REATIVIDADE VASCULAR EM ARTÉRIA AORTA DE RATOS DIABÉTICOS
  37. Valorization of Fruit Co-Product Flours for Human Nutrition: Challenges, Applications, and Perspectives
  38. Solid Lipid Nanoparticles from Platonia insignis Seeds, a Brazilian Amazon Fruit: Characterization, In Vitro and In Vivo Toxicological and Antioxidant Activities
  39. Croton cajucara: Patents and Nanotechnological Advances
  40. Effect of freezing and freeze-drying on bioactive compounds and antioxidant activity of carnauba pulp (Copernicia prunifera (Mill.) H.E. Moore)
  41. The kombucha ingestion benefits on the intestinal microbiota
  42. Association between Consumption of Ultra-Processed Food and Body Composition of Adults in a Capital City of a Brazilian Region
  43. SEMELHANÇAS E DIFERENÇAS NA NEUROPLASTICIDADE DESENCADEADA POR COCAÍNA E MORFINA
  44. Lycopene from Red Guava (Psidium guajava L.): From Hepatoprotective Effect to Its Use as Promising Self-Emulsifying Drug Delivery System for Anti-Inflammatory and Antioxidant Applications
  45. Hypokinetic Activity of Menthofuran on the Gastrointestinal Tract in Rodents
  46. The (–)-Borneol Effect on Addiction/Abstinence by Morphine in Mice
  47. 11 ANOS DE NOTIFICAÇÕES SOBRE INTOXICAÇÕES EXÓGENAS REGISTRADAS NO SINAN PELO ESTADO DO PIAUÍ
  48. Ozonation of Cowpea Grains: Alternative for the Control of Callosobruchus maculatus and Maintenance of Grain Quality
  49. Association between Polyphenol Intake and Lipid Profile of Adults and Elders in a Northeastern Brazilian Capital
  50. Riparin-B as a Potential Inhibitor of AdeABC Efflux System from Acinetobacter baumannii
  51. Antioxidant Mechanisms Underlying the Gastroprotective Effect of Menthofuran on Experimentally Induced Gastric Lesions in Rodents
  52. Avaliação toxicológica após administração aguda de uma manteiga industrializada obtida a partir das sementes do bacuri (Platonia insignis Mart.)
  53. Drug development, Brazilian biodiversity and political choices: Where are we heading?
  54. Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
  55. Novel Scaffold Based on Chitosan Hydrogels/Phthalated Cashew Gum for Supporting Human Dental Pulp Stem Cells
  56. Influence of Plant Age on Chemical Composition, Antimicrobial Activity and Cytotoxicity of Varronia curassavica Jacq. Essential Oil Produced on an Industrial Scale
  57. Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene
  58. Anxiolytic/Sedative Effect of Monoterpene (–)-Borneol in Mice and In Silico Molecular Interaction with GABAA Receptor
  59. R-(+)-Limoneno e seu derivado (–)-Carveol: uma revisão de seus efeitos sobre o diabetes
  60. Production and Characterization of a β-Cyclodextrin Inclusion Complex with Platonia insignis Seed Extract as a Proposal for a Gastroprotective System
  61. Isopropyl Gallate, a Gallic Acid Derivative: In Silico and In Vitro Investigation of Its Effects on Leishmania major
  62. Cryolipolysis on More than One Body Area Increases Lipid Peroxidation without Changing Lipid Profile and Inflammatory Markers
  63. Systematic Mapping of the Production Chain of “Bacuri” (Platonia insignis Mart.) in Brazil
  64. The Platonia insignis Mart. as the Promising Brazilian ‘Amazon Gold’: The State-of-the-Art and Prospects
  65. Perspectives on the Therapeutic Effects of Pelvic Floor Electrical Stimulation: A Systematic Review
  66. Effects of zinc supplementation on glycemic control and oxidative stress in experimental diabetes: A systematic review
  67. Amoxicillin-Resistant Streptococci Carriage in the Mouths of Children: A Systematic Review and Meta-Analysis
  68. Modulation of Drug Resistance by Furanochromones in NorA Overexpressing Staphylococcus Aureus
  69. Antiulcerogenic and Antibacterial Effects of Chitosan Derivatives on Experimental Gastric Ulcers in Rats
  70. Bioactive Natural Products against Systemic Arterial Hypertension: A Past 20-Year Systematic and Prospective Review
  71. Effect of fortification of extender with α‐terpineol and rosemary essential oil on post‐thaw ovine semen quality
  72. The Health Effects of Dietary Supplements
  73. Anti-Inflammatory and Antioxidant Effects of the Indole-Derived N-Salicyloyltryptamine on Peritonitis and Joint Disability Induced by Carrageenan in Rodents
  74. The Isopropyl Gallate Counteracts Cyclophosphamide-Induced Hemorrhagic Cystitis in Mice
  75. Hypotriglyceridemic and hepatoprotective effect of pumpkin (Cucurbita moschata) seed flour in an experimental model of dyslipidemia
  76. Effects of “Bacuri” Seed Butter (Platonia insignis Mart.), a Brazilian Amazon Fruit, on Oxidative Stress and Diabetes Mellitus-Related Parameters in STZ-Diabetic Rats
  77. Rhodiola rosea: main features and its beneficial properties
  78. Effects of ω-3 PUFA-Rich Oil Supplementation on Cardiovascular Morphology and Aortic Vascular Reactivity of Adult Male Rats Submitted to an Hypercholesterolemic Diet
  79. Effects of Fish Oil Supplementation on Oxidative Stress Biomarkers and Liver Damage in Hypercholesterolemic Rats
  80. Methods of macrophages activation and their modulation for the prospection of new antileishmania drugs: a review
  81. Effects of “Bacuri” Seed Butter (Platonia insignis Mart.) on Metabolic Parameters in Hamsters with Diet-Induced Hypercholesterolemia
  82. Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells
  83. A importância dos ensaios de toxicidade para o desenvolvimento e o registro de fitoterápicos no Brasil
  84. Biflavones from Platonia insignis Mart. Flowers Promote In Vitro Antileishmanial and Immunomodulatory Effects against Internalized Amastigote Forms of Leishmania amazonensis
  85. Limonene-carvacrol: A combination of monoterpenes with enhanced antileishmanial activity
  86. Selective in vitro antileishmanial activity of Mimosa caesalpiniifolia stem barks and its main constituent betulinic acid against Leishmania amazonensis
  87. Antiparasitic Properties of Cardiovascular Agents against Human Intravascular Parasite Schistosoma mansoni
  88. Flavonoides isolados de Sida santaremnensis H. Monteiro (“Guanxuma”) e avaliação das atividades biológicas
  89. Formulações tópicas à base de manteiga das sementes de Platonia insignis Mart. para o tratamento de lesões relacionadas à leishmaniose cutânea experimental
  90. Anti-Leishmania activity of extracts from Piper cabralanum C.DC. (Piperaceae)
  91. Pirfenidone Is a Vasodilator: Involvement of KV7 Channels in the Effect on Endothelium-Dependent Vasodilatation in Type-2 Diabetic Mice
  92. EVIDÊNCIAS SOBRE O USO DOS ÁCIDOS GRAXOS ÔMEGA-3 NO TRATAMENTO DAS DISLIPIDEMIAS
  93. Plant-Derived Butters as Lipid Nanocarriers: A Systematic and Prospective Review
  94. The authors reply
  95. Gallic and Ellagic acids: Promising adjuvants to conventional amphotericin B for the treatment of cutaneous leishmaniasis
  96. Acetylcholinesterase inhibition prevents alterations in cardiovascular autonomic control and gastric motility in L-NAME-induced hypertensive rats
  97. Terlipressin Increases Systemic and Lowers Pulmonary Arterial Pressure in Experimental Acute Pulmonary Embolism
  98. Garcinielliptone FC: Selective anti-amastigote and immunomodulatory effects on macrophages infected by Leishmania amazonensis
  99. 3-O-Acyl triterpenoids and antileishmanial effect of the ethanolic extract from Mimosa caesalpiniifolia inflorescences
  100. Silver nanoparticle stabilized by hydrolyzed collagen and natural polymers: Synthesis, characterization and antibacterial-antifungal evaluation
  101. Antimicrobial activity of Mimosa caesalpiniifolia Benth and its interaction with antibiotics against Staphylococcus aureus strains overexpressing efflux pump genes
  102. Copper nanoparticles stabilized with cashew gum: Antimicrobial activity and cytotoxicity against 4T1 mouse mammary tumor cell line
  103. Lycopene-Rich Extract from Red Guava (Psidium guajava L.) Decreases Plasma Triglycerides and Improves Oxidative Stress Biomarkers on Experimentally-Induced Dyslipidemia in Hamsters
  104. Different mechanisms involved in liraglutide and glucagon‐like peptide‐1 vasodilatation in rat mesenteric small arteries
  105. Pharmaceutical development of tablets containing a spray-dried optimized extract from Lippia origanoides H. B. K.: influence of excipients and toxicological assessment
  106. Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells
  107. Antiedematogenic activity of the indole derivative N-salicyloyltryptamine in animal models
  108. Lycopene-rich extract from red guava ( Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway
  109. Correlations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients—A Clinical Perspective Study
  110. Structure-function studies of BPP-BrachyNH 2 and synthetic analogues thereof with Angiotensin I-Converting Enzyme
  111. Antileishmanial and Immunomodulatory Effects of Dermaseptin-01, A Promising Peptide Against Leishmania amazonensis
  112. Gallic and ellagic acids: two natural immunomodulator compounds solve infection of macrophages by Leishmania major
  113. Anti-Leishmania activity of essential oil of Myracrodruon urundeuva (Engl.) Fr. All.: Composition, cytotoxity and possible mechanisms of action
  114. Synergistic effects of in vitro combinations of piplartine, epiisopiloturine and praziquantel against Schistosoma mansoni
  115. Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation
  116. Chitosan-based silver nanoparticles: A study of the antibacterial, antileishmanial and cytotoxic effects
  117. In Silico, In Vitro and In Vivo Toxicological Assessment of BPP-BrachyNH2, A Vasoactive Proline-Rich Oligopeptide from Brachycephalus ephippium
  118. In VitroEffects of the Neolignan 2,3-Dihydrobenzofuran AgainstLeishmania Amazonensis
  119. Inhibitory effects of Zanthoxylum rhoifolium Lam. (Rutaceae) against the infection and infectivity of macrophages by Leishmania amazonensis
  120. Mechanisms Involved in Thromboxane A2-induced Vasoconstriction of Rat Intracavernous Small Penile Arteries
  121. Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest
  122. A Novel Vasoactive Proline-Rich Oligopeptide from the Skin Secretion of the Frog Brachycephalus ephippium
  123. Optimization and standardization of extraction method from Lippia origanoides H.B.K.: Focus on potential anti-hypertensive applications
  124. Involvement of Potassium Channels and Calcium-Independent Mechanisms in Hydrogen Sulfide-Induced Relaxation of Rat Mesenteric Small Arteries
  125. Hypotensive and vasorelaxant effects induced by the ethanolic extract of the Mimosa caesalpiniifolia Benth. (Mimosaceae) inflorescences in normotensive rats
  126. Pharmacological Evidence of α2-Adrenergic Receptors in the Hypotensive Effect of Platonia insignis Mart.
  127. Garcinielliptone FC, a polyisoprenylated benzophenone fromPlatonia insignisMart., promotes vasorelaxant effect on rat mesenteric artery
  128. Chemical constituents and toxicological studies of leaves from Mimosa caesalpiniifolia Benth., a Brazilian honey plant
  129. Phytochemical Prospection and Modulation of Antibiotic Activity In Vitro byLippia origanoidesH.B.K. in Methicillin ResistantStaphylococcus aureus
  130. Brazilian brown propolis elicits antileishmanial effect against promastigote and amastigote forms ofLeishmania amazonensis
  131. Gastroprotective activity of Cenostigma macrophyllum Tul. var. acuminata Teles Freire leaves on experimental ulcer models
  132. Gastroprotective Effect of an Ethanolic Extract from Neoglaziovia variegata (Arruda) Mez (Bromeliaceae) in Rats and Mice
  133. Anti-Inflammatory and Anti-Ulcer Activities of Carvacrol, a Monoterpene Present in the Essential Oil of Oregano
  134. Multiple origins of the western European house mouse in the Aeolian Archipelago: clues from mtDNA and chromosomes
  135. Bioactivity evaluation against Artemia salina Leach of medicinal plants used in Brazilian Northeastern folk medicine
  136. Vasorelaxant response induced by Sida santaremnensis H. Monteiro ethanol extract on rat superior mesenteric artery
  137. Investigation of Mechanisms Involved in (−)-Borneol-Induced Vasorelaxant Response on Rat Thoracic Aorta
  138. Variabilidade sazonal dos constituintes da própolis vermelha e bioatividade em Artermia salina