All Stories

  1. The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
  2. Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
  3. Ribonucleotide Reductase Regulatory Subunit M2 as a Driver of Glioblastoma TMZ-Resistance through Modulation of dNTP Production
  4. TRPM2 Non-Selective Cation Channels in Liver Injury Mediated by Reactive Oxygen Species
  5. Effects of nerol on paracetamol-induced liver damage in Wistar albino rats
  6. Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment
  7. De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma
  8. mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
  9. Targeting Ca2+ Signaling in the Initiation, Promotion and Progression of Hepatocellular Carcinoma
  10. ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
  11. Deranged hepatocyte intracellular Ca2+ homeostasis and the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma
  12. Abstract 81: ARL13B interacts with IMPDH2 to modulate purine synthesis and temozolomide resistance in glioblastoma
  13. Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides
  14. Calcium Signaling As a Therapeutic Target for Liver Steatosis
  15. Effect of Diets, Familial History, and Alternative Therapies on Genomic Instability of Breast Cancer Patients
  16. Evidence for the interaction of peroxiredoxin-4 with the store-operated calcium channel activator STIM1 in liver cells
  17. Correlations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients—A Clinical Perspective Study
  18. Assessment of chemotherapy on various biochemical markers in breast cancer patients
  19. Metabolic Disorders and Cancer: Hepatocyte Store-Operated Ca2+ Channels in Nonalcoholic Fatty Liver Disease
  20. Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens
  21. The glucagon-like peptide-1 analogue exendin-4 reverses impaired intracellular Ca 2+ signalling in steatotic hepatocytes
  22. Steatosis inhibits liver cell store-operated Ca2+ entry and reduces ER Ca2+ through a protein kinase C-dependent mechanism
  23. An in silico virtual screening study for the design of norovirus inhibitors: fragment-based molecular docking and binding free energy calculations
  24. Associations between Arsenic Exposure and Global Posttranslational Histone Modifications among Adults in Bangladesh