All Stories

  1. Pan-tumor harmonization of pathologic response assessment for standardized data collection in neoadjuvant trials (PATHdata): results of a Society for Immunotherapy of Cancer multi-institutional reproducibility study

    Article • Annals of Oncology, May 2026, Elsevier

    Christian M Schuerch

  2. B7-H3 (CD276) as Target for T Cell-Based Bispecific Antibody Therapy of Penile Cancer

    Article • ImmunoTargets and Therapy, May 2026, Taylor & Francis

    Christian M Schuerch

  3. CD70/CD27 signaling promotes the pathogenesis of multiple myeloma and represents a promising therapeutic target

    Article • Leukemia, March 2026, Springer Science + Business Media

    Christian M Schuerch

  4. Updated pan-tumor guidelines for neoadjuvant scoring of pathologic response: a joint SITC and INMC effort

    Article • Annals of Oncology, February 2026, Elsevier

    Christian M Schuerch

  5. Modeling patient tissues at molecular resolution with Eva

    Article • December 2025, openRxiv

    Christian M Schuerch

  6. Erythropoietin receptor on cDC1s dictates immune tolerance

    Article • Nature, December 2025, Springer Science + Business Media

    Christian M Schuerch

  7. Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer

    Article • Nature Communications, October 2025, Springer Science + Business Media

    Christian M Schuerch

  8. Mixed acinar cell carcinoma/non-ampullary adenocarcinoma of the duodenum

    Article • Pathology, October 2025, Elsevier

    Christian M Schuerch

  9. Studying therapy effects and disease outcomes in silico using artificial counterfactual tissue samples

    Article • Computers in Biology and Medicine, October 2025, Elsevier

    Christian M Schuerch

  10. A Validation Workflow for Novel Oligonucleotide Sequences to Expand the Multiplexing Capacity of the CO-Detection by indEXing (CODEX) Platform

    Article • Laboratory Investigation, October 2025, Elsevier

    Christian M Schuerch

  11. Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma

    Article • Developmental Cell, October 2025, Elsevier

    Christian M Schuerch

  12. Real-world data of azacitidine for relapsed/refractory nodal T-follicular helper cell lymphoma in 11 patients

    Article • Frontiers in Hematology, September 2025, Frontiers

    Christian M Schuerch

  13. PathoCellBench: A Comprehensive Benchmark for Cell Phenotyping

    Article • September 2025, Springer Science + Business Media

    Christian M Schuerch

  14. ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images

    Article • Nature Communications, August 2025, Springer Science + Business Media

    Christian M Schuerch

  15. B7-H3: a consistent marker in metastatic colorectal cancer with potential for targeted treatment

    Article • Pathology & Oncology Research, August 2025, Frontiers

    Christian M Schuerch

  16. Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study

    Article • Journal of Medical Internet Research, July 2025, JMIR Publications Inc.

    Christian M Schuerch

  17. PET-based immunomapping of intratumoral CD4 + cells to monitor acquired resistance to checkpoint inhibitors

    Article • Science Advances, June 2025, American Association for the Advancement of Science

    Christian M Schuerch

  18. Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett’s esophagus through progression to cancer

    Article • June 2025, openRxiv

    Christian M Schuerch

  19. MCSP+ metastasis founder cells activate immunosuppression early in human melanoma metastatic colonization

    Article • Nature Cancer, May 2025, Springer Science + Business Media

    Christian M Schuerch

  20. The extra-islet pancreas supports autoimmunity in human type 1 diabetes

    Article • eLife, April 2025, eLife

    Christian M Schuerch

  21. The extra-islet pancreas supports autoimmunity in human type 1 diabetes

    Article • eLife, April 2025, eLife

    Christian M Schuerch

  22. High-dimensional imaging using combinatorial channel multiplexing and deep learning

    Article • Nature Biotechnology, March 2025, Springer Science + Business Media

    Christian M Schuerch

  23. Liver cancer recurrence predicted by immune-cell location and gene expression

    Article • Nature, March 2025, Springer Science + Business Media

    Christian M Schuerch

  24. Implementing digital pathology: qualitative and financial insights from eight leading European laboratories

    Article • Virchows Archiv, March 2025, Springer Science + Business Media

    Christian M Schuerch

  25. Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas

    Article • British Journal of Dermatology, February 2025, Oxford University Press (OUP)

    Christian M Schuerch

  26. Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects

    Article • Gastro Hep Advances, January 2025, Elsevier

    Christian M Schuerch

  27. Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment

    Article • December 2024, openRxiv

    Christian M Schuerch

  28. ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images

    Article • November 2024, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  29. Collagen fleece grafting for surgical treatment of patients with mild to severe peyronie’s curvatures

    Article • International Urology and Nephrology, October 2024, Springer Science + Business Media

    Christian M Schuerch

  30. Targeting CD276 for T cell-based immunotherapy of breast cancer

    Article • Journal of Translational Medicine, October 2024, Springer Science + Business Media

    Christian M Schuerch

  31. Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade

    Article • American Review of Respiratory Disease, October 2024, Oxford University Press (OUP)

    Christian M Schuerch

  32. Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study (Preprint)

    Article • June 2024, JMIR Publications Inc.

    Christian M Schuerch

  33. Pan-tumor harmonization of pathologic response assessment for standardized data collection in neoadjuvant IO trials (PATHdata): Final analysis of a multi-institutional reproducibility study.

    Article • Journal of Clinical Oncology, June 2024, American Society of Clinical Oncology (ASCO)

    Christian M Schuerch

  34. Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment

    Article • March 2024, openRxiv

    Christian M Schuerch

  35. :Crossing the Boundaries of Life: Günter Blobel and the Origins of Molecular Cell Biology

    Article • Isis, March 2024, University of Chicago Press

    Christian M Schuerch

  36. Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning

    Article • February 2024, Springer Science + Business Media

    Christian M Schuerch

  37. Auswirkungen vorgeschalteter Laborprozesse auf die Digitalisierung histologischer Schnittpräparate

    Article • Die Pathologie, February 2024, Springer Science + Business Media

    Christian M Schuerch

  38. Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities

    Article • Nature Cell Biology, February 2024, Springer Science + Business Media

    Christian M Schuerch

  39. A replicating LCMV-based vaccine for the treatment of solid tumors

    Article • Molecular Therapy, February 2024, Elsevier

    Christian M Schuerch

  40. Histological and functional characterization of 3D human skin models mimicking the inflammatory skin diseases psoriasis and atopic dermatitis

    Article • Disease Models & Mechanisms, January 2024, The Company of Biologists

    Christian M Schuerch

  41. Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data

    Article • iScience, December 2023, Elsevier

    Christian M Schuerch

  42. CD70/CD27 Signaling Promotes Expansion of Clonal Plasma Cells in Multiple Myeloma and Is a Promising Therapeutic Target in Advanced Disease

    Article • Blood, November 2023, American Society of Hematology

    Christian M Schuerch

  43. Spatial Dissection of the Bone Marrow Microenvironment in Multiple Myeloma By High Dimensional Multiplex Tissue Imaging

    Article • Blood, November 2023, American Society of Hematology

    Christian M Schuerch

  44. EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy

    Article • Journal of the American Academy of Dermatology, November 2023, Elsevier

    Christian M Schuerch

  45. Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer

    Article • Cancer Cell, November 2023, Elsevier

    Christian M Schuerch

  46. Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes

    Article • Cell Reports, October 2023, Elsevier

    Christian M Schuerch

  47. Corrigendum: A review on deep learning applications in highly multiplexed tissue imaging data analysis

    Article • Frontiers in Bioinformatics, September 2023, Frontiers

    Christian M Schuerch

  48. Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning

    Article • September 2023, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  49. S3-CIMA: Supervised spatial single-cell image analysis for identifying disease-associated cell-type compositions in tissue

    Article • Patterns, September 2023, Elsevier

    Christian M Schuerch

  50. Translational data from a multicenter phase II study on dimethyl fumarate treatment in relapsed and refractory cutaneous T cell lymphoma

    Article • European Journal of Cancer, September 2023, Elsevier

    Christian M Schuerch

  51. Dimethyl fumarate treatment in relapsed and refractory cutaneous T-cell lymphoma: a multicenter phase 2 study

    Article • Blood, August 2023, American Society of Hematology

    Christian M Schuerch

  52. Case Report: Paraneoplastic psoriasis in thymic carcinoma

    Article • Frontiers in Oncology, August 2023, Frontiers

    Christian M Schuerch

  53. Impact of P-selectin–PSGL-1 Axis on Platelet-Endothelium-Leukocyte Interactions in Fatal COVID-19

    Article • Laboratory Investigation, August 2023, Elsevier

    Christian M Schuerch

  54. A review on deep learning applications in highly multiplexed tissue imaging data analysis

    Article • Frontiers in Bioinformatics, July 2023, Frontiers

    Christian M Schuerch

  55. Organization of the human intestine at single-cell resolution

    Article • Nature, July 2023, Springer Science + Business Media

    Christian M Schuerch

  56. Expanded vacuum-stable gels for multiplexed high-resolution spatial histopathology

    Article • Nature Communications, July 2023, Springer Science + Business Media

    Christian M Schuerch

  57. Concerted epithelial and stromal changes during progression of Barrett’s Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis

    Article • June 2023, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  58. EGFR expression and relapse in patients with melanoma receiving adjuvant PD-1-based immunotherapy.

    Article • Journal of Clinical Oncology, June 2023, American Society of Clinical Oncology (ASCO)

    Christian M Schuerch

  59. S3-CIMA: Supervised spatial single-cell image analysis for the identification of disease-associated cell type compositions in tissue

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  60. The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  61. Comprehensive analysis of SARS‐CoV‐2 receptor proteins in human respiratory tissues identifies alveolar macrophages as potential virus entry site

    Article • Histopathology, February 2023, Wiley

    Christian M Schuerch

  62. Towards multiomic analysis of oral mucosal pathologies

    Article • Seminars in Immunopathology, February 2023, Springer Science + Business Media

    Christian M Schuerch

  63. High-multiplex tissue imaging in routine pathology—are we there yet?

    Article • Virchows Archiv, February 2023, Springer Science + Business Media

    Christian M Schuerch

  64. Implementing deep learning models for the classification of Echinococcus multilocularis infection in human liver tissue

    Article • Parasites & Vectors, January 2023, Springer Science + Business Media

    Christian M Schuerch

  65. A tissue atlas of ulcerative colitis revealing evidence of sex-dependent differences in disease-driving inflammatory cell types and resistance to TNF inhibitor therapy

    Article • Science Advances, January 2023, American Association for the Advancement of Science

    Christian M Schuerch

  66. Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma

    Article • Nature Communications, January 2023, Springer Science + Business Media

    Christian M Schuerch

  67. SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages

    Article • Science Translational Medicine, December 2022, American Association for the Advancement of Science

    Christian M Schuerch

  68. Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities

    Article • November 2022, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  69. Charakterisierung des Tumormikromilieus mittels Hochmultiplexmikroskopieverfahren

    Article • Die Pathologie, October 2022, Springer Science + Business Media

    Christian M Schuerch

  70. Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

    Article • Cancer Cell International, October 2022, Springer Science + Business Media

    Christian M Schuerch

  71. Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance

    Article • Leukemia, September 2022, Springer Science + Business Media

    Christian M Schuerch

  72. Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV

    Article • Brain, July 2022, Oxford University Press (OUP)

    Christian M Schuerch

  73. Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery

    Article • Science Advances, July 2022, American Association for the Advancement of Science

    Dr. Marie-Françoise Ritz, Christian M Schuerch

  74. A single cell spatial temporal atlas of skeletal muscle reveals cellular neighborhoods that orchestrate regeneration and become disrupted in aging

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  75. Tissue schematics map the specialization of immune tissue motifs and their appropriation by tumors

    Article • Cell Systems, February 2022, Elsevier

    Christian M Schuerch

  76. Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  77. CellSeg: a robust, pre-trained nucleus segmentation and pixel quantification software for highly multiplexed fluorescence images

    Article • BMC Bioinformatics, January 2022, Springer Science + Business Media

    Christian M Schuerch

  78. Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans

    Article • Respiration, January 2022, Karger Publishers

    Christian M Schuerch

  79. Rhesus Macaque CODEX Multiplexed Immunohistochemistry Panel for Studying Immune Responses During Ebola Infection

    Article • Frontiers in Immunology, December 2021, Frontiers

    Christian M Schuerch

  80. Human influenza virus challenge identifies cellular correlates of protection for oral vaccination

    Article • Cell Host & Microbe, December 2021, Elsevier

    Christian M Schuerch

  81. High Resolution Single Cell Maps Reveals Distinct Cell Organization and Function Across Different Regions of the Human Intestine

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  82. Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

    Article • Nature Communications, November 2021, Springer Science + Business Media

    Christian M Schuerch

  83. Diagnostic and Prognostic Implications of Caspase-1 and PD-L1 Co-Expression Patterns in Myelodysplastic Syndromes

    Article • Cancers, November 2021, MDPI AG

    Christian M Schuerch

  84. Molecular Progression of Myeloproliferative and Myelodysplastic/Myeloproliferative Neoplasms: A Study on Sequential Bone Marrow Biopsies

    Article • Cancers, November 2021, MDPI AG

    Christian M Schuerch

  85. SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  86. Multiples Myelom aus Sicht der Pathologie

    Article • Der Radiologe, October 2021, Springer Science + Business Media

    Christian M Schuerch

  87. Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers

    Article • Cell Reports Medicine, October 2021, Elsevier

    Christian M Schuerch

  88. Supporting the Next Generation of Scientists to Lead Cancer Immunology Research

    Article • Cancer Immunology Research, September 2021, American Association for Cancer Research (AACR)

    Christian M Schuerch, Felix Hartmann

  89. Tracing tumor evolution and subtype specification in pancreatic cancer

    Article • August 2021, Springer Science + Business Media

    Christian M Schuerch

  90. CODEX multiplexed tissue imaging with DNA-conjugated antibodies

    Article • Nature Protocols, July 2021, Springer Science + Business Media

    Christian M Schuerch

  91. Virtual and augmented reality for biomedical applications

    Article • Cell Reports Medicine, July 2021, Elsevier

    Christian M Schuerch

  92. Diversity, localization, and (patho)physiology of mature lymphocyte populations in the bone marrow

    Article • Blood, June 2021, American Society of Hematology

    Christian M Schuerch

  93. Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging

    Article • Frontiers in Immunology, May 2021, Frontiers

    Christian M Schuerch

  94. Electrospray Mediated Localized and Targeted Chemotherapy in a Mouse Model of Lung Cancer

    Article • Frontiers in Pharmacology, April 2021, Frontiers

    Christian M Schuerch

  95. Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction

    Article • European Journal of Immunology, March 2021, Wiley

    Christian M Schuerch

  96. A tissue atlas of ulcerative colitis to guide TNF inhibitor therapy

    Article • February 2021, Springer Science + Business Media

    Christian M Schuerch

  97. Nanoscopic subcellular imaging enabled by ion beam tomography

    Article • Nature Communications, February 2021, Springer Science + Business Media

    Christian M Schuerch

  98. SARS-CoV-2 entry factors are expressed in nasal, ocular, and oral tissues: implications for COVID-19 prophylaxes/therapeutics

    Article • Journal of Allergy and Clinical Immunology, February 2021, Elsevier

    Christian M Schuerch

  99. Author Correction: Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity

    Article • Nature Communications, January 2021, Springer Science + Business Media

    Christian M Schuerch

  100. Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength

    Article • Science, January 2021, American Association for the Advancement of Science

    Christian M Schuerch

  101. Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

    Article • January 2021, Springer Science + Business Media

    Christian M Schuerch

  102. Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells

    Article • Cell Reports, January 2021, Elsevier

    Christian M Schuerch

  103. Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  104. Abstract PO-036: Defining the role of chromatin remodelers in pancreatic cancer

    Article • Cancer Research, November 2020, American Association for Cancer Research (AACR)

    Christian M Schuerch

  105. ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs

    Article • Nature Communications, October 2020, Springer Science + Business Media

    Christian M Schuerch

  106. Landscape of coordinated immune responses to H1N1 challenge in humans

    Article • Journal of Clinical Investigation, October 2020, American Society for Clinical Investigation

    Christian M Schuerch

  107. Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

    Article • Cell, October 2020, Elsevier

    Christian M Schuerch

  108. O3 High-dimensional analysis of tumor architecture predicts cancer immunotherapy response

    Article • October 2020, BMJ

    Christian M Schuerch

  109. Expression of SARS-CoV-2 entry receptors in the respiratory tract of healthy individuals, smokers and asthmatics

    Article • Respiratory Research, September 2020, Springer Science + Business Media

    Christian M Schuerch

  110. Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

    Article • Cell, September 2020, Elsevier

    Christian M Schuerch

  111. Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection

    Article • Cell Metabolism, September 2020, Elsevier

    Christian M Schuerch

  112. Abstract 6669: Cellular neighborhoods predict pembrolizumab response in cutaneous T cell lymphoma

    Article • Cancer Research, August 2020, American Association for Cancer Research (AACR)

    Christian M Schuerch

  113. PET Imaging of the Natural Killer Cell Activation Receptor NKp30

    Article • Journal of Nuclear Medicine, June 2020, Society of Nuclear Medicine

    Christian M Schuerch

  114. Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  115. Bispecific Antibodies for Multiple Myeloma: A Review of Targets, Drugs, Clinical Trials, and Future Directions

    Article • Frontiers in Immunology, April 2020, Frontiers

    Christian M Schuerch

  116. Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Christian M Schuerch

  117. TNIK signaling imprints CD8+ T cell memory formation early after priming

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Christian M Schuerch

  118. Functional comparison of PBMCs isolated by Cell Preparation Tubes (CPT) vs. Lymphoprep Tubes

    Article • BMC Immunology, March 2020, Springer Science + Business Media

    Christian M Schuerch

  119. A review on tumor heterogeneity and evolution in multiple myeloma: pathological, radiological, molecular genetics, and clinical integration

    Article • Virchows Archiv, December 2019, Springer Science + Business Media

    Christian M Schuerch

  120. CD93-Signaling Regulates Self-Renewal and Proliferation of Chronic Myeloid Leukemia Stem Cells in Mice and Humans and Might be a Promising Target for Treatment

    Article • Blood, November 2019, American Society of Hematology

    Christian M Schuerch

  121. Dynamics of the Cutaneous T Cell Lymphoma Microenvironment in Patients Treated with Pembrolizumab Revealed By Highly Multiplexed Tissue Imaging

    Article • Blood, November 2019, American Society of Hematology

    Christian M Schuerch

  122. Splenic CD24low Red Pulp Macrophages Provide an Alternate Niche for Chronic Myeloid Leukemia Stem Cells

    Article • Blood, November 2019, American Society of Hematology

    Christian M Schuerch

  123. Lobular neoplasia and invasive lobular breast cancer: Inter-observer agreement for histological grading and subclassification

    Article • Pathology - Research and Practice, November 2019, Elsevier

    Florian Laenger, Christian M Schuerch

  124. The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

    Article • Nature, October 2019, Springer Science + Business Media

    Christian M Schuerch

  125. Coordinated cellular neighborhoods orchestrate antitumoral immunity at the colorectal cancer invasive front

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  126. P12.09 Multidimensional Personalized Response Assessment to Microglia Modulators in Gioblastoma Bioreactors

    Article • Neuro-Oncology, August 2019, Oxford University Press (OUP)

    Christian M Schuerch

  127. Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy

    Article • Thyroid, July 2019, Mary Ann Liebert Inc

    Christian M Schuerch

  128. CARving up colorectal cancer organoids in vitro

    Article • Genes & Immunity, May 2019, Springer Science + Business Media

    Christian M Schuerch

  129. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma

    Article • Cell, April 2019, Elsevier

    Christian M Schuerch

  130. Ion beam subcellular tomography

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Christian M Schuerch

  131. Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

    Article • SSRN Electronic Journal, January 2019, Elsevier

    Christian M Schuerch

  132. Dynamics of the Bone Marrow Microenvironment during Leukemic Progression Revealed By Codex Hyper-Parameter Tissue Imaging

    Article • Blood, November 2018, American Society of Hematology

    Christian M Schuerch

  133. Therapeutic Antibodies for Myeloid Neoplasms—Current Developments and Future Directions

    Article • Frontiers in Oncology, May 2018, Frontiers

    Christian M Schuerch

  134. The “don't eat me” signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma

    Article • OncoImmunology, September 2017, Taylor & Francis

    Christian M Schuerch

  135. Tumor Heterogeneity in Lymphomas: A Different Breed

    Article • Pathobiology, July 2017, Karger Publishers

    Christian M Schuerch

  136. How mechanisms explain interfield cooperation: biological–chemical study of plant growth hormones in Utrecht and Pasadena, 1930–1938

    Article • History & Philosophy of the Life Sciences, July 2017, Springer Science + Business Media

    Christian M Schuerch

  137. Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity

    Article • PLoS Pathogens, June 2017, PLOS

    Christian M Schuerch

  138. The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34 + Stem/Progenitor Cells

    Article • Molecular Cancer Therapeutics, May 2017, American Association for Cancer Research (AACR)

    Christian M Schuerch

  139. CD70/CD27 signaling promotes blast stemness and is a viable therapeutic target in acute myeloid leukemia

    Article • Journal of Experimental Medicine, December 2016, Rockefeller University Press

    Christian M Schuerch

  140. Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model

    Article • Frontiers in Cellular and Infection Microbiology, December 2016, Frontiers

    Christian M Schuerch

  141. Tyrosine kinase inhibitor-induced CD70 expression mediates drug resistance in leukemia stem cells by activating Wnt signaling

    Article • Science Translational Medicine, July 2015, American Association for the Advancement of Science

    Christian M Schuerch

  142. CD47 protein expression in acute myeloid leukemia: A tissue microarray-based analysis

    Article • Leukemia Research, July 2015, Elsevier

    Christian M Schuerch

  143. IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms

    Article • Journal of Clinical Investigation, May 2015, American Society for Clinical Investigation

    Christian M Schuerch

  144. Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells

    Article • Leukemia, February 2015, Nature

    Christian M Schuerch

  145. CD70/CD27 Signaling Mediates Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors By Compensatory Activation of the Wnt Pathway

    Article • Blood, December 2014, American Society of Hematology

    Christian M Schuerch

  146. Microbiota-Derived Compounds Drive Steady-State Granulopoiesis via MyD88/TICAM Signaling

    Article • The Journal of Immunology, October 2014, The American Association of Immunologists

    Christian M Schuerch

  147. Regulation of hematopoietic and leukemic stem cells by the immune system

    Article • Cell Death and Differentiation, July 2014, Nature

    Christian M Schuerch

  148. Cytotoxic CD8+ T Cells Stimulate Hematopoietic Progenitors by Promoting Cytokine Release from Bone Marrow Mesenchymal Stromal Cells

    Article • Cell Stem Cell, April 2014, Elsevier

    Christian M Schuerch

  149. TREM-1 Deficiency Can Attenuate Disease Severity without Affecting Pathogen Clearance

    Article • PLoS Pathogens, January 2014, PLOS

    Christian M Schuerch, Manfred Kopf

  150. Interferons in hematopoiesis and leukemia

    Article • OncoImmunology, June 2013, Taylor & Francis

    Christian M Schuerch

  151. “Leiomyomatoid angiomatous neuroendocrine tumor” (LANT) of the pituitary reflects idiosyncratic angiogenesis in adenomas of the gonadotroph cell lineage

    Article • Pathology - Research and Practice, March 2013, Elsevier

    Christian M Schuerch

  152. Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ

    Article • Journal of Experimental Medicine, February 2013, Rockefeller University Press

    Christian M Schuerch

  153. From "magic bullets" to specific cancer immunotherapy

    Article • Swiss Medical Weekly, January 2013, EMH Swiss Medical Publishers, Ltd.

    Christian M Schuerch

  154. Dendritic Cell-Based Immunotherapy for Myeloid Leukemias

    Article • Frontiers in Immunology, January 2013, Frontiers

    Christian M Schuerch

  155. Modulating CD27 signaling to treat cancer

    Article • OncoImmunology, December 2012, Taylor & Francis

    Christian M Schuerch

  156. CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth

    Article • Cancer Research, May 2012, American Association for Cancer Research (AACR)

    Christian M Schuerch

  157. CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression

    Article • Journal of Clinical Investigation, February 2012, American Society for Clinical Investigation

    Christian M Schuerch

  158. Destruction of Lymphoid Organ Architecture and Hepatitis Caused by CD4+ T Cells

    Article • PLOS One, September 2011, PLOS

    Christian M Schuerch

  159. Chronic myelogenous leukemia maintains specific CD8+ T cells through IL-7 signaling

    Article • European Journal of Immunology, July 2010, Wiley

    Christian M Schuerch

  160. Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression

    Article • Blood, May 2009, American Society of Hematology

    Christian M Schuerch

  161. Defective homing and impaired induction of cytotoxic T cells by BCR/ABL-expressing dendritic cells

    Article • Blood, February 2009, American Society of Hematology

    Christian M Schuerch

  162. Prevention of Brain Injury by the Nonbacteriolytic Antibiotic Daptomycin in Experimental Pneumococcal Meningitis

    Article • Antimicrobial Agents and Chemotherapy, March 2007, ASM Journals

    Christian M Schuerch