All Stories

  1. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Dr Mario M Dorostkar

  2. Translocator protein (18kDa) TSPO: a new diagnostic or therapeutic target for stress-related disorders?

    Article • Molecular Psychiatry, April 2022, Springer Science + Business Media

    Dr Mario M Dorostkar

  3. Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)

    Article • Nature Neuroscience, February 2022, Springer Science + Business Media

    Dr Mario M Dorostkar

  4. Anaplastic pleomorphic xanthoastrocytoma with epithelioid morphology misdiagnosed and treated as melanoma

    Article • Neuro-Oncology Advances, January 2022, Oxford University Press (OUP)

    Dr Mario M Dorostkar

  5. Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations

    Article • Acta Neuropathologica, January 2021, Springer Science + Business Media

    Dr Mario M Dorostkar

  6. Extent and prognostic value of MGMT promotor methylation in glioma WHO grade II

    Article • Scientific Reports, November 2020, Springer Science + Business Media

    Dr Mario M Dorostkar

  7. Molecular characterization of histopathological ependymoma variants

    Article • Acta Neuropathologica, November 2019, Springer Science + Business Media

    Dr Mario M Dorostkar

  8. Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy

    Article • Acta Neuropathologica, August 2019, Springer Science + Business Media

    Dr Mario M Dorostkar

  9. Tcf4 regulates dendritic spine density and morphology in the adult brain

    Article • PLoS ONE, June 2018, PLOS

    Dr Mario M Dorostkar

  10. K27M midline gliomas display malignant progression by imaging and histology

    Article • Neuropathology and Applied Neurobiology, July 2017, Wiley

    Dr Mario M Dorostkar

  11. High plasticity of axonal pathology in Alzheimer’s disease mouse models

    Article • Acta Neuropathologica Communications, February 2017, Springer Science + Business Media

    Dr Mario M Dorostkar

  12. Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6

    Article • Biological Psychiatry, December 2016, Elsevier

    Dr Mario M Dorostkar

  13. Dendritic Spine Pathology in Neurodegenerative Diseases

    Article • Annual Review of Pathology Mechanisms of Disease, May 2016, Annual Reviews

    Dr Mario M Dorostkar

  14. Distinct Histomorphology in Molecular Subgroups of Glioblastomas in Young Patients

    Article • Journal of Neuropathology & Experimental Neurology, March 2016, Oxford University Press (OUP)

    Dr Mario M Dorostkar

  15. Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease

    Article • Acta Neuropathologica, January 2016, Springer Science + Business Media

    Dr Mario M Dorostkar

  16. δ Subunit-containing GABAA receptors are preferred targets for the centrally acting analgesic flupirtine

    Article • British Journal of Pharmacology, October 2015, Wiley

    Dr Mario M Dorostkar

  17. Miliary pattern of brain metastases – a case report of a hyperacute onset in a patient with malignant melanoma documented by magnetic resonance imaging

    Article • Radiation Oncology, July 2015, Springer Science + Business Media

    Dr Mario M Dorostkar

  18. Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

    Article • Acta Neuropathologica, June 2015, Springer Science + Business Media

    Dr Mario M Dorostkar

  19. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer’s disease

    Article • Acta Neuropathologica, April 2015, Springer Science + Business Media

    Dr Mario M Dorostkar

  20. Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model

    Article • Brain, October 2014, Oxford University Press (OUP)

    Dr Mario M Dorostkar

  21. Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin

    Article • Molecular Psychiatry, June 2014, Nature

    Dr Mario M Dorostkar

  22. Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb

    Article • Nature Communications, May 2014, Nature

    Dr Mario M Dorostkar

  23. In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques

    Article • Acta Neuropathologica Communications, January 2014, Springer Science + Business Media

    Dr Mario M Dorostkar

  24. Constitutive activation of β-Catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system

    Article • Developmental Biology, February 2013, Elsevier

    Dr Mario M Dorostkar

  25. Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice

    Article • Acta Neuropathologica Communications, January 2013, Springer Science + Business Media

    Dr Mario M Dorostkar

  26. Arc illuminates Alzheimer's pathophysiology

    Article • Nature Neuroscience, September 2012, Nature

    Dr Mario M Dorostkar

  27. Amyloid plaque formation precedes dendritic spine loss

    Article • Acta Neuropathologica, September 2012, Springer Science + Business Media

    Dr Mario M Dorostkar

  28. Concomitant facilitation of GABAA receptors and KV7 channels by the non‐opioid analgesic flupirtine

    Article • British Journal of Pharmacology, June 2012, Wiley

    Professor Stefan Boehm, Dr Mario M Dorostkar

  29. 4D in in vivo 2-photon laser scanning fluorescence microscopy with sample motion in 6 degrees of freedom

    Article • Journal of Neuroscience Methods, August 2011, Elsevier

    Dr Mario M Dorostkar

  30. In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

    Article • Acta Neuropathologica, December 2010, Springer Science + Business Media

    Dr Mario M Dorostkar

  31. Computational processing of optical measurements of neuronal and synaptic activity in networks

    Article • Journal of Neuroscience Methods, April 2010, Elsevier

    Dr Mario M Dorostkar

  32. A genetically encoded reporter of synaptic activity in vivo

    Article • Nature Methods, November 2009, Nature

    Dr Mario M Dorostkar

  33. Physical and Functional Interaction between the Dopamine Transporter and the Synaptic Vesicle Protein Synaptogyrin-3

    Article • Journal of Neuroscience, April 2009, Society for Neuroscience

    Dr Mario M Dorostkar

  34. Opposite effects of presynaptic 5-HT3receptor activation on spontaneous and action potential-evoked GABA release at hippocampal synapses

    Article • Journal of Neurochemistry, January 2007, Wiley

    Dr Mario M Dorostkar

  35. The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

    Article • The Journal of Cell Biology, January 2006, Rockefeller University Press

    Dr Mario M Dorostkar

  36. The Ubiquitin-Specific Protease Usp4 Regulates the Cell Surface Level of the A2a Receptor

    Article • Molecular Pharmacology, December 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Mario M Dorostkar

  37. Serotonin-transporter mediated efflux: A pharmacological analysis of amphetamines and non-amphetamines

    Article • Neuropharmacology, November 2005, Elsevier

    Dr Mario M Dorostkar

  38. Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y12 receptor-mediated inhibition of voltage-gated Ca2+ channels

    Article • European Journal of Neuroscience, December 2004, Wiley

    Dr Mario M Dorostkar

  39. Two Discontinuous Segments in the Carboxyl Terminus Are Required for Membrane Targeting of the Rat  -Aminobutyric Acid Transporter-1 (GAT1)

    Article • Journal of Biological Chemistry, April 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Mario M Dorostkar