All Stories

  1. Coriander seed oil extract abrogates hepatic biochemical and histopathological alterations associated with acrylamide intoxication in rats
  2. Green synthesized selenium nanoparticles using Trigonellafoenum–graecum exhibit antioxidant and anti-inflammatory effects against acetaminophen-induced nephrotoxicity in mice
  3. Moringa oleifera extract and rutin prevent monosodium glutamate-induced nephrotoxicity in rats
  4. Diosmin-loaded chitosan nanoparticles mitigate doxorubicin-evoked cardiotoxicity in rats by featuring oxidative imbalance mechanism, NF-κB, and Bcl-2/Bax pathways
  5. Dual inhibition strategy addressing hyperuricemia and oxidative stress: design, biological evaluation and stability studies of febuxostat-probenecid mutual prodrug
  6. Evaluation of Vincamine Loaded with Silver Nanoparticles as a New Potential Therapeutic Agent Against Ehrlich’s Solid Carcinoma in Mice
  7. Holothuria polii Extract as a Potential Anticoccidial Agent: Evidence of Its MUC2 Regulatory Impact in Murine Jejunum
  8. Intermittent fasting alerts neurotransmitters and oxidant/antioxidant status in the brain of rats
  9. Fighting sepsis‐induced liver damage with biosynthesized silver nanoparticles
  10. Leek (Allium ampeloprasum var. kurrat) aqueous extract loaded on selenium nanoparticles protects against testis and brain injury induced by mercuric chloride in rats
  11. Zinc Oxide Nanoparticles Attenuated Neurochemical and Histopathological Alterations Associated with Aluminium Chloride Intoxication in Rats
  12. Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis
  13. Unraveling the immune response of the spleen in sepsis using green‐synthesized silver nanoparticles from pomegranate peel extracts
  14. Short‐term immunotoxicity induced by florpyrauxifen‐benzyl herbicide exposure in the spleen of male albino mice
  15. Turmeric Extract-loaded Selenium Nanoparticles Counter Doxorubicin-induced Hepatotoxicity in Mice via Repressing Oxidative Stress, Inflammatory Cytokines, and Cell Apoptosis
  16. Green-Synthesized Silver and Selenium Nanoparticles Using Berberine: A Comparative Assessment of In Vitro Anticancer Potential on Human Hepatocellular Carcinoma Cell Line (HepG2)
  17. Editorial: Hot topic: anti-inflammatory drug discovery
  18. Resistomycin Suppresses Prostate Cancer Cell Growth by Instigating Oxidative Stress, Mitochondrial Apoptosis, and Cell Cycle Arrest
  19. Coenzyme Q10-Loaded Albumin Nanoparticles Protect against Redox Imbalance and Inflammatory, Apoptotic, and Histopathological Alterations in Mercuric Chloride-Induced Hepatorenal Toxicity in Rats
  20. Modulation of inflammatory, oxidative, and apoptotic stresses mediates the renoprotective effect of daidzein against glycerol-induced acute kidney injury in rats
  21. Therapeutic activity of green synthesized selenium nanoparticles from turmeric against cisplatin-induced oxido-inflammatory stress and cell death in mice kidney
  22. A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different Antioxidants
  23. Nephroprotective Efficacy of Echinops spinosus against a Glycerol-Induced Acute Kidney Injury Model
  24. Therapeutic role of mesenchymal stem cells and platelet-rich plasma on skin burn healing and rejuvenation: A focus on scar regulation, oxido-inflammatory stress and apoptotic mechanisms
  25. Biosynthesized Selenium Nanoparticles Using Epigallocatechin Gallate Protect against Pentylenetetrazole-Induced Acute Epileptic Seizures in Mice via Antioxidative, Anti-Inflammatory, and Anti-Apoptotic Activities
  26. The Potential Therapeutic Role of Green-Synthesized Selenium Nanoparticles Using Carvacrol in Human Breast Cancer MCF-7 Cells
  27. Towards the Development of Dual Hypouricemic and Anti-inflammatory Candidates: Design, Synthesis, Stability Studies and Biological Evaluation of Some Mutual Ester Prodrugs of Febuxostat-NSAIDs
  28. Biochemical and histopathological effects of copper oxide nanoparticles exposure on the bivalve Chambardia rubens (Lamarck, 1819)
  29. Neuro-amelioration of Ficus lyrata (fiddle-leaf fig) extract conjugated with selenium nanoparticles against aluminium toxicity in rat brain: relevance to neurotransmitters, oxidative, inflammatory, and apoptotic events
  30. Green Coffee Bean Extract Potentially Ameliorates Liver Injury due to HFD/STZ-Induced Diabetes in Rats
  31. Green Synthetized Selenium Nanoparticles Using Syzygium aromaticum (Clove) Extract Reduce Pentylenetetrazol-Induced Epilepsy and Associated Cortical Damage in Rats
  32. Rutin-loaded selenium nanoparticles modulated the redox status, inflammatory, and apoptotic pathways associated with pentylenetetrazole-induced epilepsy in mice
  33. Apigenin protects from hepatorenal damage caused by lead acetate in rats
  34. Antioxidant capacity of N-acetylcysteine against the molecular and cytotoxic implications of cadmium chloride leading to hepatotoxicity and vital progression
  35. The Neuroprotective Effect Associated with Echinops spinosus in an Acute Seizure Model Induced by Pentylenetetrazole
  36. Therapeutic antischizophrenic activity of prodigiosin and selenium co-supplementation against amphetamine hydrochloride-induced behavioural changes and oxidative, inflammatory, and apoptotic challenges in rats
  37. Silver Nanoparticles Enhance Oxidative Stress, Inflammation, and Apoptosis in Liver and Kidney Tissues: Potential Protective Role of Thymoquinone
  38. Evaluation of the antineoplastic property of prodigiosins and 5-fluorouracil in restraining the growth of Ehrlich solid tumors in mice
  39. Antitumor Activity of Zinc Nanoparticles Synthesized with Berberine on Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cells through Acting on Cox-2/NF-kB and p53 Pathways
  40. Evaluation of antiobesity and hepatorenal protective activities of Salvia officinalis extracts pre-treatment in high-fat diet-induced obese rats
  41. Apigenin attenuates molecular, biochemical, and histopathological changes associated with renal impairments induced by gentamicin exposure in rats
  42. Anticolitic activity of prodigiosin loaded with selenium nanoparticles on acetic acid–induced colitis in rats
  43. Selenium Nanoparticles with Prodigiosin Rescue Hippocampal Damage Associated with Epileptic Seizures Induced by Pentylenetetrazole in Rats
  44. Potential of green-synthesized selenium nanoparticles using apigenin in human breast cancer MCF-7 cells
  45. Apigenin attenuates molecular, biochemical, and histopathological changes associated with renal impairments induced by gentamicin exposure in rats
  46. Echinops spinosus effect against diabetes and its hepatorenal complications: total extract and flavonoids fraction
  47. Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries
  48. Green-synthetized selenium nanoparticles using berberine as a promising anticancer agent
  49. Chlororesistoflavins A and B, Chlorinated Benzopyrene Antibiotics Produced by the Marine-Derived Actinomycete Streptomyces sp. Strain EG32
  50. Neuroprotective Efficiency of Prodigiosins Conjugated with Selenium Nanoparticles in Rats Exposed to Chronic Unpredictable Mild Stress is Mediated Through Antioxidative, Anti-Inflammatory, Anti-Apoptotic, and Neuromodulatory Activities
  51. Aluminum Chloride–Induced Reproductive Toxicity in Rats: the Protective Role of Zinc Oxide Nanoparticles
  52. Neuroprotective effect of green and roasted coffee bean extracts on cerebral ischemia-induced injury in rats
  53. Zingerone mitigates inflammation, apoptosis and oxidative injuries associated with renal impairment in adriamycin-intoxicated mice
  54. Evaluation of the potential role of silver nanoparticles loaded with berberine in improving anti-tumor efficiency
  55. Lycopene mitigates arsenic-induced nephrotoxicity with activation of the Nrf2 pathway in mice
  56. The protective role of luteolin against the methotrexate-induced hepato-renal toxicity via its antioxidative, anti-inflammatory, and anti-apoptotic effects in rats
  57. N-Acetylcysteine Reduces miR-146a and NF-κB p65 Inflammatory Signaling Following Cadmium Hepatotoxicity in Rats
  58. Ziziphus spina-christi Leaf Extract Mitigates Mercuric Chloride-induced Cortical Damage in Rats
  59. The Protective Effects of Melatonin on Aluminum-Induced Hepatotoxicity and Nephrotoxicity in Rats
  60. Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
  61. The Potential Protective Effect of Orange Peel and Selenium against 17β-Estradiol- Induced Chronic Non-Bacterial Prostatitis in Rats
  62. <p>Selenium Nanoparticles Pre-Treatment Reverse Behavioral, Oxidative Damage, Neuronal Loss and Neurochemical Alterations in Pentylenetetrazole-Induced Epileptic Seizures in Mice</p>
  63. Nephroprotective effects of chlorogenic acid against sodium arsenite‐induced oxidative stress, inflammation, and apoptosis
  64. Green Coffea arabica Extract Ameliorates Testicular Injury in High-Fat Diet/Streptozotocin-Induced Diabetes in Rats
  65. Impact of Coenzyme Q10 Administration on Lead Acetate-Induced Testicular Damage in Rats
  66. Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis
  67. Arg753Gln Polymorphisms in the Toll-Like Receptor 2 Gene are Associated with Cytomegalovirus Infection in Egyptian Bone Marrow Recipients
  68. Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice
  69. Neuroprotective role of luteolin against lead acetate-induced cortical damage in rats
  70. Luteolin protects against lead acetate-induced nephrotoxicity through antioxidant, anti-inflammatory, anti-apoptotic, and Nrf2/HO-1 signaling pathways
  71. Saussurea lappa root extract ameliorates the hazards effect of thorium induced oxidative stress and neuroendocrine alterations in adult male rats
  72. Myristica fragrans seed extract reverses scopolamine-induced cortical injury via stimulation of HO-1 expression in male rats
  73. Antagonistic Efficacy of Luteolin against Lead Acetate Exposure-Associated with Hepatotoxicity is Mediated via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Activities
  74. The Potential Role of Zinc Oxide Nanoparticles in MicroRNAs Dysregulation in STZ-Induced Type 2 Diabetes in Rats
  75. Ziziphus spina-christi leaf extract attenuates mercury chloride-induced testicular dysfunction in rats
  76. Anti-Inflammatory and Anti-Hyperuricemic Functions of Two Synthetic Hybrid Drugs with Dual Biological Active Sites
  77. Triggering of apoptosis and cell cycle arrest by fennel and clove oils in Caco-2 cells: the role of combination
  78. The Neuroprotective Role of Coenzyme Q10 Against Lead Acetate-Induced Neurotoxicity Is Mediated by Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities
  79. Prodigiosins from a marine sponge-associated actinomycete attenuate HCl/ethanol-induced gastric lesion via antioxidant and anti-inflammatory mechanisms
  80. Potential role of N-acetylcysteine on chlorpyrifos-induced neurotoxicity in rats
  81. Candelariella vitellina extract triggers in vitro and in vivo cell death through induction of apoptosis: A novel anticancer agent
  82. Anti-Toxoplasma activity of silver nanoparticles green synthesized with Phoenix dactylifera and Ziziphus spina-christi extracts which inhibits inflammation through liver regulation of cytokines in Balb/c mice
  83. Royal jelly attenuates cadmium-induced nephrotoxicity in male mice
  84. Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy
  85. Myristica fragrans Kernels Prevent Paracetamol-Induced Hepatotoxicity by Inducing Anti-Apoptotic Genes and Nrf2/HO-1 Pathway
  86. Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice
  87. Royal Jelly Abrogates Cadmium-Induced Oxidative Challenge in Mouse Testes: Involvement of the Nrf2 Pathway
  88. Antitumor Potential of Berberine and Cinnamic Acid against Solid Ehrlich Carcinoma in Mice
  89. Royal jelly mitigates cadmium-induced neuronal damage in mouse cortex
  90. Ziziphus spina-christi leaf extract ameliorates schistosomiasis liver granuloma, fibrosis, and oxidative stress through downregulation of fibrinogenic signaling in mice
  91. Ziziphus spina-christi (L.) leaf extract alleviates myocardial and renal dysfunction associated with sepsis in mice
  92. Clinical Efficacy Associated with Enhanced Antioxidant Enzyme Activities of Silver Nanoparticles Biosynthesized Using Moringa oleifera Leaf Extract, Against Cutaneous Leishmaniasis in a Murine Model of Leishmania major
  93. Ziziphus spina-christi fruit extract suppresses oxidative stress and p38 MAPK expression in ulcerative colitis in rats via induction of Nrf2 and HO-1 expression
  94. Ganoderma applanatum secondary metabolites induced apoptosis through different pathways: In vivo and in vitro anticancer studies
  95. Evaluation of the Protective Effect of Olive Leaf Extract on Cisplatin-Induced Testicular Damage in Rats
  96. Ziziphus spina-christi leaf extract pretreatment inhibits liver and spleen injury in a mouse model of sepsis via anti-oxidant and anti-inflammatory effects
  97. Pomegranate (Punica granatum) Juice Shows Antioxidant Activity against Cutaneous Leishmaniasis-Induced Oxidative Stress in Female BALB/c Mice
  98. Olive ( Olea europaea ) leaf methanolic extract prevents HCl/ethanol-induced gastritis in rats by attenuating inflammation and augmenting antioxidant enzyme activities
  99. Protective Effects of Fragaria ananassa Extract Against Cadmium Chloride-Induced Acute Renal Toxicity in Rats
  100. Oral Mucositis: Melatonin Gel an Effective New Treatment
  101. Protective Effect of Fragaria ananassa Crude Extract on Cadmium-Induced Lipid Peroxidation, Antioxidant Enzymes Suppression, and Apoptosis in Rat Testes
  102. Melatonin protects rats from radiotherapy-induced small intestine toxicity
  103. Oral Mucositis: Melatonin Gel an Effective New Treatment
  104. Protective effect of Fragaria ananassa methanolic extract on cadmium chloride (CdCl2)-induced hepatotoxicity in rats
  105. Erratum to: Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress
  106. Antifibrotic candidates of Selenium nanoparticles and selenium in the experimental model
  107. Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats
  108. Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress
  109. Pre-Clinical Study for the Antidiabetic Potential of Selenium Nanoparticles
  110. The Protective Properties of the Strawberry (Fragaria ananassa) against Carbon Tetrachloride-Induced Hepatotoxicity in Rats Mediated by Anti-Apoptotic and Upregulation of Antioxidant Genes Expression Effects
  111. Indigofera oblongifolia Prevents Lead Acetate-Induced Hepatotoxicity, Oxidative Stress, Fibrosis and Apoptosis in Rats
  112. Indigofera oblongifolia mitigates lead-acetate-induced kidney damage and apoptosis in a rat model
  113. Indigofera oblongifolia Ameliorates Lead Acetate-Induced Testicular Oxidative Damage and Apoptosis in a Rat Model
  114. Medicinal Plants in Therapy: Antioxidant Activities
  115. Neuroprotective potential of Indigofera oblongifolia leaf methanolic extract against lead acetate-induced neurotoxicity
  116. Anti-hyperglycemic activity of selenium nanoparticles in streptozotocin-induced diabetic rats
  117. A spiroketal-enol ether derivative from Tanacetum vulgare selectively inhibits HSV-1 and HSV-2 glycoprotein accumulation in Vero cells
  118. Histological, molecular and biochemical detection of renal injury after Echis pyramidum snake envenomation in rats
  119. Low-dose γ rays prevents DMH-induced colon cancer
  120. Oxidant/Antioxidant Imbalance and the Risk of Alzheimer's Disease
  121. The protective properties of melatonin against aluminium-induced neuronal injury
  122. Protective effects of melatonin against oxidative damage induced by Egyptian cobra (Naja haje) crude venom in rats
  123. The neuroprotective effect of berberine in mercury-induced neurotoxicity in rats
  124. Mercury-induced neurotoxicity and neuroprotective effects of berberine
  125. The potential protective role of Physalis peruviana L. fruit in cadmium-induced hepatotoxicity and nephrotoxicity
  126. Prevention of carbon tetrachloride (CCl4)-induced toxicity in testes of rats treated with Physalis peruviana L. fruit
  127. Citrus Peel Extract Attenuates Acute Cyanide Poisoning-Induced Seizures and Oxidative Stress in Rats
  128. Neuroprotective Effects of Citrus reticulata in Scopolamine-Induced Dementia Oxidative Stress in Rats
  129. The Protective Effect of Physalis peruviana L. Against Cadmium-Induced Neurotoxicity in Rats
  130. Biological effects of Naja haje crude venom on the hepatic and renal tissues of mice
  131. The potential effect of berberine in mercury-induced hepatorenal toxicity in albino rats
  132. Testing the Genotoxicity, Cytotoxicity, and Oxidative Stress of Cadmium and Nickel and Their Additive Effect in Male Mice
  133. Protective effects of pomegranate (Punica granatum) juice on testes against carbon tetrachloride intoxication in rats
  134. Effect of Physalis peruviana L. on Cadmium-Induced Testicular Toxicity in Rats
  135. Azadirachta indica attenuates cisplatin-induced neurotoxicity in rats
  136. Azadirachta indica Attenuates Cisplatin-Induced Nephrotoxicity
  137. Hepatotoxicity and oxidative stress induced by Naja haje crude venom
  138. The Potential Protective Effect ofPhysalis peruvianaL. against Carbon Tetrachloride-Induced Hepatotoxicity in Rats Is Mediated by Suppression of Oxidative Stress and Downregulation of MMP-9 Expression
  139. Pomegranate peel attenuates aluminum-induced hepatorenal toxicity
  140. The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat
  141. THERAPEUTIC ACTIVITY OF BEE-STINGS THERAPY IN RHEUMATOID ARTHRITIS CAUSES INFLAMMATION AND OXIDATIVE STRESS IN FEMALE PATIENTS
  142. Hepatic oxidative stress in Mongolian gerbils experimentally infected with Babesia divergens
  143. The potential role of Portulaca oleracea as a neuroprotective agent in rotenone-induced neurotoxicity and apoptosis in the brain of rats
  144. The Potential Role ofAzadirachta indicaTreatment on Cisplatin-Induced Hepatotoxicity and Oxidative Stress in Female Rats
  145. The potential effects of pomegranate (Punica granatum) juice on carbon tetrachloride-induced nephrotoxicity in rats
  146. Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis
  147. Evaluating the Potential Role of Pomegranate Peel in Aluminum-Induced Oxidative Stress and Histopathological Alterations in Brain of Female Rats
  148. Protective effects of Portulaca oleracea against rotenone mediated depletion of glutathione in the striatum of rats as an animal model of Parkinson’s disease
  149. Studies on the effect of Salvia aegyptiaca and Trigonella foenum graecum extracts on adult male mice
  150. Neuronal activities of Portulaca oleracea
  151. Flaxseed Oil as a Neuroprotective Agent on Lead Acetate-Induced Monoamineric Alterations and Neurotoxicity in Rats
  152. Antioxidant activities of Punica granatum (pomegranate) peel extract on brain of rats
  153. The protective effect of flaxseed oil on lead acetate-induced renal toxicity in rats
  154. Effects of Flaxseed Oil on Lead Acetate-Induced Neurotoxicity in Rats
  155. The Redox Status in Rats Treated with Flaxseed Oil and Lead-Induced Hepatotoxicity