All Stories

  1. Implications of the 2024 American Heart Association Classification of Cardiac Sarcoidosis: Characteristics and Outcome of Patients Across the Continuum of Diagnostic Likelihood
  2. Immunophenotypic characterization of bone marrow residing in peripheral artery atherosclerotic plaques
  3. Natural History of Patients With Histologically Proven Acute Eosinophilic Myocarditis
  4. Myocardial sympathetic distal axon loss in subjects with Lewy pathology: an artificial intelligence‐based histopathological analysis
  5. Variability in arteriolosclerosis in different brain regions: An AI‐based population study of the Oldest‐Old (Vantaa85+)
  6. Microscopic cardiac pathology in forensic autopsies: a comparative study of anabolic androgenic steroid users and non-users
  7. Intranodal expansion of follicular T helper cells in patients with multiple sclerosis
  8. Myocardial sympathetic distal axon loss in subjects with Lewy pathology in three autopsy cohorts
  9. Predicting Anabolic Androgenic Steroid Doping among Specialized Health Care Patients with Elastic Net Regression Reveals Potential Laboratory Variables for “Patient Biological Passport”
  10. Parvovirus B19 and Human Herpes Virus 6B and 7 Are Frequently Found DNA Viruses in the Human Thymus But Show No Definitive Link With Myasthenia Gravis
  11. Endomyocardial biopsy in the diagnosis of cardiac sarcoidosis
  12. LATE‐NC IN THE VERY ELDERLY– THE POPULATION‐BASED VANTAA 85+ ‐STUD
  13. Reduction in mucosal‐associated invariant T cells (MAIT) in APECED patients is associated with elevated serum IFN‐γ concentration
  14. Lung Cancer in Finland
  15. Infective SARS-CoV-2 in Skull Sawdust at Autopsy, Finland
  16. Limbic-predominant age-related TDP-43 encephalopathy in the oldest old: a population-based study
  17. Increased type 1 inflammation in gynecologic cervicovaginal samples in patients with APS-1
  18. Dysregulated germinal center reaction with expanded T follicular helper cells in autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy lymph nodes
  19. Prediction model for anabolic androgenic steroid positivity in forensic autopsy cases – a new tool to the autopsy room
  20. Association of anabolic androgenic steroid use with perimortem polypharmacy, antemortem prescription drug use, and utilization of health care services – A Finnish triple register study of forensic autopsy cases
  21. Mucosal-Associated Invariant T Cells are not susceptible in vitro to SARS-CoV-2 infection but accumulate into the lungs of COVID-19 patients
  22. A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer
  23. Vascular adhesion protein-1-targeted PET imaging in autoimmune myocarditis
  24. Cardiac Death
  25. Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors
  26. Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer
  27. Female doping: observations from a data lake study in the Hospital District of Helsinki and Uusimaa, Finland
  28. Data from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  29. Data from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  30. Supplementary Data from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  31. Supplementary Data from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  32. Supplementary Table S1 from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  33. Supplementary Table S1 from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  34. Supplementary Table S2 from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  35. Supplementary Table S2 from Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify <i>Kras</i>-Mutant Lung Cancers
  36. Novel therapeutic approaches for pleural mesothelioma identified by functional ex vivo drug sensitivity testing
  37. Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis
  38. Pubertal development and hypogonadism in males with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy: a retrospective study
  39. Cardiac magnetic resonance in histologically proven eosinophilic myocarditis
  40. Deep Learning Neural Network-Guided Detection of Asbestos Bodies in Bronchoalveolar Lavage Samples
  41. High relative amount of nodular calcification in femoral plaques is associated with milder lower extremity arterial disease
  42. Neutrophil proteinase 3 — An LDL- and HDL-proteolyzing enzyme with a potential to contribute to cholesterol accumulation in human atherosclerotic lesions
  43. Protocol to utilize fresh uncultured human lung tumor cells for personalized functional diagnostics
  44. Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure
  45. Epicardial transplantation of autologous atrial appendage micrografts: evaluation of safety and feasibility in pigs after coronary artery occlusion
  46. Cardiac sarcoidosis and giant cell myocarditis after COVID‐19 infection
  47. Glutamine synthetase in human carotid plaque macrophages associates with features of plaque vulnerability: An immunohistological study
  48. Prognostic Role of Tumor Immune Microenvironment in Pleural Epithelioid Mesothelioma
  49. Alterations of Cardiac Protein Kinases in Cyclic Nucleotide-Dependent Signaling Pathways in Human Ischemic Heart Failure
  50. APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study
  51. Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells
  52. GRINL1A Complex Transcription Unit Containing GCOM1, MYZAP, and POLR2M Genes Associates with Fully Penetrant Recessive Dilated Cardiomyopathy
  53. Heart Transplantation for Early-Onset Anthracycline-Induced Cardiomyopathy Within 5 Months of Chemotherapy Completion
  54. Epicardial transplantation of autologous atrial appendage micrografts–evaluation of safety and feasibility in pigs after coronary artery occlusion
  55. Severe Spontaneous Atherosclerosis in two Korat Breed Cats is Comparable to Human Atherosclerosis
  56. Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
  57. Warfarin Treatment Is Associated to Increased Internal Carotid Artery Calcification
  58. SOX9 has distinct roles in the formation and progression of different non‐small cell lung cancer histotypes
  59. Lysophosphatidylcholine in phospholipase A2-modified LDL triggers secretion of angiopoietin 2
  60. High tumor cell platelet‐derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma
  61. Manifestations and Outcome of Cardiac Sarcoidosis and Idiopathic Giant Cell Myocarditis by 25‐Year Nationwide Cohorts
  62. Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells
  63. Artificial intelligence identifies inflammation and confirms fibroblast foci as prognostic tissue biomarkers in idiopathic pulmonary fibrosis
  64. Osteoid Metaplasia in Femoral Artery Plaques Is Associated With the Clinical Severity of Lower Extremity Artery Disease in Men
  65. Predictive Factors for Pre-operative Recurrence of Cerebrovascular Symptoms in Symptomatic Carotid Stenosis
  66. Clinical Features in Patients With Malignant Pleural Mesothelioma With 5-Year Survival and Evaluation of Original Diagnoses
  67. Neuropathologic features of four autopsied COVID‐19 patients
  68. Idiopathic giant cell myocarditis or cardiac sarcoidosis? A retrospective audit of a nationwide case series
  69. Folate Receptor β–Targeted PET Imaging of Macrophages in Autoimmune Myocarditis
  70. Histopathological features of epithelioid malignant pleural mesotheliomas in patients with extended survival
  71. Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras-Mutant Lung Cancers
  72. Sudden death in cardiac sarcoidosis: an analysis of nationwide clinical and cause-of-death registries
  73. Outcome of Cardiac Sarcoidosis Presenting With High-Grade Atrioventricular Block
  74. Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques – Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2)
  75. Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras -driven lung tumours
  76. Human mast cell neutral proteases generate modified LDL particles with increased proteoglycan binding
  77. TET2 mutations in B cells of patients affected by angioimmunoblastic T-cell lymphoma
  78. Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1
  79. p38δ MAPKHighlights
  80. Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm
  81. Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome
  82. TRIF adaptor signaling is important in abdominal aortic aneurysm formation
  83. Lipoprotein-associated lipids accumulate in distinctive domains in atherosclerotic arteries.
  84. Low-Expression Variant of Fatty Acid–Binding Protein 4 Favors Reduced Manifestations of Atherosclerotic Disease and Increased Plaque Stability
  85. VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
  86. Osbpl8 Deficiency in Mouse Causes an Elevation of High-Density Lipoproteins and Gender-Specific Alterations of Lipid Metabolism
  87. Imatinib mesylate alleviates diarrhea in a mouse model of intestinal allergy
  88. Serine protease inhibitor A3 in atherosclerosis and aneurysm disease
  89. Mast Cells
  90. Increased expression of leukotriene C4synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm
  91. OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi–late endosome interface
  92. Vascular Endothelial Growth Factor–Secreting Mast Cells and Myofibroblasts
  93. Dilated cardiomyopathy alters the expression patterns of CAR and other adenoviral receptors in human heart
  94. Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms
  95. Rab8 Regulates ABCA1 Cell Surface Expression and Facilitates Cholesterol Efflux in Primary Human Macrophages
  96. ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model
  97. Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves
  98. The R-Ras interaction partner ORP3 regulates cell adhesion
  99. OSBP-related Protein 8 (ORP8) Suppresses ABCA1 Expression and Cholesterol Efflux from Macrophages
  100. Receptors for the anaphylatoxins C3a and C5a are expressed in human atherosclerotic coronary plaques
  101. Bone densitometry in the diagnosis of vertebral fractures in children: Accuracy of vertebral fracture assessment
  102. Mast cells in vulnerable atherosclerotic plaques – a view to a kill
  103. Complement regulation in human atherosclerotic coronary lesions
  104. Improved Identification of Endothelial Erosion by Simultaneous Detection of Endothelial Cells (CD31/CD34) and Platelets (CD42b)
  105. Desquamation of human coronary artery endothelium by human mast cell proteases: implications for plaque erosion
  106. Endothelial Apoptosis Does Not Determine Symptom Status in Carotid Artery Disease
  107. Increased Expression of Elastolytic Cathepsins S, K, and V and Their Inhibitor Cystatin C in Stenotic Aortic Valves
  108. Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology
  109. Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves
  110. Increased expression of bradykinin type-1 receptors in endothelium of intramyocardial coronary vessels in human failing hearts
  111. Induction of local angiotensin II-producing systems in stenotic aortic valves
  112. Cysteine Protease Cathepsin F Is Expressed in Human Atherosclerotic Lesions, Is Secreted by Cultured Macrophages, and Modifies Low Density Lipoprotein Particlesin Vitro
  113. Arterial endothelial denudation by intraluminal use of papaverine–NaCl solution in coronary bypass surgery
  114. Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
  115. Down-regulation of cardioprotective bradykinin type-2 receptors in the left ventricle of patients with end-stage heart failure