All Stories

  1. Mechanochemical Reductive Amination of Aldehydes and Ketones: Solid-State Synthesis of the Antiparkinsonian Drugs Rasagiline and Safinamide

    Article • ACS Sustainable Chemistry & Engineering, November 2025, American Chemical Society (ACS)

    J. Carlos Menéndez

  2. 2-Styrylquinolines with Push-Pull Architectures as Sensors for β-Amyloid Aggregation with Theranostic Properties

    Article • International Journal of Molecular Sciences, August 2025, MDPI AG

    J. Carlos Menéndez

  3. Regioselective N-2 Alkylation of Tetrazoles with Phenacyl Halides under Mechanochemical Conditions and Its Application to a Solid-State Synthesis of the Antiepileptic Drug Cenobamate

    Article • ACS Sustainable Chemistry & Engineering, May 2025, American Chemical Society (ACS)

    J. Carlos Menéndez

  4. Network-Based Drug Optimization toward the Treatment of Parkinson’s Disease: NRF2, MAO-B, Oxidative Stress, and Chronic Neuroinflammation

    Article • Journal of Medicinal Chemistry, January 2025, American Chemical Society (ACS)

    J. Carlos Menéndez

  5. Twenty-first century antiepileptic drugs. An overview of their targets and synthetic approaches

    Article • European Journal of Medicinal Chemistry, June 2024, Elsevier

    J. Carlos Menéndez

  6. Dual Antitubercular and Antileishmanial Profiles of Quinoxaline Di-N-Oxides Containing an Amino Acidic Side Chain

    Article • Pharmaceuticals, April 2024, MDPI AG

    J. Carlos Menéndez

  7. Fluorimetric Detection of Insulin Misfolding by Probes Derived from Functionalized Fluorene Frameworks

    Article • Molecules, March 2024, MDPI AG

    J. Carlos Menéndez

  8. Structure-Antitumor Activity Relationships of Aza- and Diaza-Anthracene-2,9,10-Triones and Their Partially Saturated Derivatives

    Article • Molecules, January 2024, MDPI AG

    J. Carlos Menéndez

  9. Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects

    Article • Pharmaceutics, September 2023, MDPI AG

    J. Carlos Menéndez

  10. Rapid Assembly of Functionalized 2H-Chromenes and 1,2-Dihydroquinolines via Microwave-Assisted Secondary Amine-Catalyzed Cascade Annulation of 2-O/N-Propargylarylaldehydes with 2,6-Dialkylphenols

    Article • The Journal of Organic Chemistry, August 2023, American Chemical Society (ACS)

    J. Carlos Menéndez

  11. Quinones as Neuroprotective Agents

    Article • Antioxidants, July 2023, MDPI AG

    J. Carlos Menéndez

  12. m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity

    Article • Molecules, July 2023, MDPI AG

    J. Carlos Menéndez

  13. Small-molecule theranostics in Alzheimer's disease

    Article • European Journal of Medicinal Chemistry, July 2023, Elsevier

    J. Carlos Menéndez

  14. A New Method for the Introduction of an Acylsulfonamide Moiety Applied to a 3-Substituted Functionalized Indole Framework ­Related to the Welwitindolinone Alkaloids

    Article • Synlett, May 2023, Thieme Publishing Group

    J. Carlos Menéndez

  15. 2-(3-Bromophenyl)imidazo[2,1-b]oxazole

    Article • Molbank, April 2023, MDPI AG

    J. Carlos Menéndez

  16. Anticancer drugs acting on signaling pathways, part 1: Tyrosine kinase inhibitors

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  17. Anticancer drugs acting on signaling pathways, part 2: Inhibitors of serine-threonine kinases and miscellaneous signaling pathways

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  18. Anticancer drugs targeting tubulin and microtubules

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  19. Anticancer drugs that interact with the DNA minor groove

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  20. Anticancer drugs that modulate hormone action

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  21. Anticancer strategies involving radical species

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  22. Antimetabolites

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  23. Cancer chemoprevention

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  24. Cancer immunotherapy

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  25. DNA alkylating agents

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  26. DNA intercalation and topoisomerase inhibition

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  27. Drug targeting in anticancer chemotherapy

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  28. Drugs that modulate resistance to antitumor agents

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  29. Epigenetic therapy of cancer

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  30. General aspects of cancer therapy

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  31. Miscellaneous small- molecule and biological approaches to targeted cancer therapy

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  32. Protein degradation-based cancer therapy

    Article • January 2023, Elsevier

    J. Carlos Menéndez

  33. Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing

    Article • Biomedicines, September 2022, MDPI AG

    J. Carlos Menéndez

  34. An Efficient Synthesis of a Highly Functionalized Dihydrobenzo­thiophene Derivative: A Ring-Contracted Analogue of the Anti-inflammatory Drug Propoxicam

    Article • Synlett, June 2022, Thieme Publishing Group

    J. Carlos Menéndez

  35. Fluorescence Sensors Based on Hydroxycarbazole for the Determination of Neurodegeneration-Related Halide Anions

    Article • Biosensors, March 2022, MDPI AG

    J. Carlos Menéndez

  36. Approaches to the Potential Therapy of COVID-19: A General Overview from the Medicinal Chemistry Perspective

    Article • Molecules, January 2022, MDPI AG

    J. Carlos Menéndez

  37. Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157–Lipoic Acid Hybrids for the Treatment of Alzheimer’s Disease

    Article • Antioxidants, January 2022, MDPI AG

    J. Carlos Menéndez

  38. Enantioselective catalytic Povarov reactions

    Article • Organic & Biomolecular Chemistry, January 2022, Royal Society of Chemistry

    J. Carlos Menéndez

  39. Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

    Article • Antioxidants, December 2021, MDPI AG

    J. Carlos Menéndez

  40. Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation

    Article • Pharmaceutics, October 2021, MDPI AG

    J. Carlos Menéndez

  41. Mechanochemical Synthesis of Primary Amides

    Article • The Journal of Organic Chemistry, October 2021, American Chemical Society (ACS)

    J. Carlos Menéndez

  42. Neuroprotective Action of Multitarget 7-Aminophenanthridin-6(5H)-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells

    Article • ACS Chemical Neuroscience, August 2021, American Chemical Society (ACS)

    J. Carlos Menéndez

  43. Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation

    Article • Antioxidants, June 2021, MDPI AG

    J. Carlos Menéndez

  44. (2S*,4S*)-4-[(E)-(2,2-Dimethylhydrazono)methyl]-6-methoxy-4-methyl-2-[(E)-styryl]-1,2,3,4-tetrahydroquinoline

    Article • Molbank, June 2021, MDPI AG

    J. Carlos Menéndez

  45. (E)-3-((2-Fluorophenyl)(hydroxy)methylene)imidazo[1,2-a]pyridin-2(3H)-one

    Article • Molbank, May 2021, MDPI AG

    J. Carlos Menéndez

  46. Mechanochemical Aza-Vinylogous Povarov Reactions for the Synthesis of Highly Functionalized 1,2,3,4-Tetrahydroquinolines and 1,2,3,4-Tetrahydro-1,5-Naphthyridines

    Article • Molecules, March 2021, MDPI AG

    J. Carlos Menéndez

  47. Sustainable Access to Acridin-9-(10H)ones with an Embedded m-Terphenyl Moiety Based on a Three-Component Reaction

    Article • Molecules, November 2020, MDPI AG

    J. Carlos Menéndez

  48. Synthesis of 1,4-Diazepanes and Benzo[b][1,4]diazepines by a Domino Process Involving the In Situ Generation of an Aza-Nazarov Reagent

    Article • The Journal of Organic Chemistry, August 2020, American Chemical Society (ACS)

    J. Carlos Menéndez

  49. Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer’s Disease

    Article • Antioxidants, July 2020, MDPI AG

    J. Carlos Menéndez

  50. Antioxidants as Molecular Probes: Structurally Novel Dihydro-m-Terphenyls as Turn-On Fluorescence Chemodosimeters for Biologically Relevant Oxidants

    Article • Antioxidants, July 2020, MDPI AG

    J. Carlos Menéndez

  51. NRF2 Regulation Processes as a Source of Potential Drug Targets against Neurodegenerative Diseases

    Article • Biomolecules, June 2020, MDPI AG

    J. Carlos Menéndez

  52. D-Ring-Modified Analogues of Luotonin A with Reduced Planarity: Design, Synthesis, and Evaluation of Their Topoisomerase Inhibition-Associated Cytotoxicity

    Article • BioMed Research International, November 2019, Hindawi Publishing Corporation

    J. Carlos Menéndez

  53. Front Cover: Rearrangement Reactions in Aza-Vinylogous Povarov Products: Metal-Free Synthesis of C3 -Functionalized Quinolines and Studies on their Synthetic Application (Eur. J. Org. Chem. 38/2019)

    Article • European Journal of Organic Chemistry, September 2019, Wiley

    J. Carlos Menéndez, Professor Pedro Merino

  54. Proline and its Derivatives as Organocatalysts for Multi‐ Component Reactions in Aqueous Media: Synergic Pathways to the Green Synthesis of Heterocycles

    Article • Advanced Synthesis & Catalysis, September 2019, Wiley

    J. Carlos Menéndez

  55. Rearrangement Reactions in Aza-Vinylogous Povarov Products: Metal-Free Synthesis of C3 -Functionalized Quinolines and Studies on their Synthetic Application

    Article • European Journal of Organic Chemistry, August 2019, Wiley

    J. Carlos Menéndez, Professor Pedro Merino

  56. Design and synthesis of A- and D ring-modified analogues of luotonin A with reduced planarity

    Article • Tetrahedron Letters, June 2019, Elsevier

    J. Carlos Menéndez

  57. Spirooxindole-pyrrolidine heterocyclic hybrids promotes apoptosis through activation of caspase-3

    Article • Bioorganic & Medicinal Chemistry, June 2019, Elsevier

    J. Carlos Menéndez

  58. Structure-activity relationships and mechanistic studies of novel mitochondria-targeted, leishmanicidal derivatives of the 4-aminostyrylquinoline scaffold

    Article • European Journal of Medicinal Chemistry, June 2019, Elsevier

    J. Carlos Menéndez

  59. Progress in the Chemistry of Tetrahydroquinolines

    Article • Chemical Reviews, April 2019, American Chemical Society (ACS)

    J. Carlos Menéndez

  60. Diversity‐Oriented Synthesis of Complex Pyrrole‐Based Architectures from Very Simple Starting Materials

    Article • Advanced Synthesis & Catalysis, March 2019, Wiley

    J. Carlos Menéndez

  61. Multicomponent domino protocol for the stereoselective synthesis of novel pyrrolo[3,2-c]quinolinone hybrid heterocycles

    Article • Tetrahedron Letters, February 2019, Elsevier

    J. Carlos Menéndez

  62. Heterogeneous Amberlyst-15-catalyzed synthesis of complex hybrid heterocycles containing [1,6]-naphthyridine under metal-free green conditions

    Article • Organic & Biomolecular Chemistry, January 2019, Royal Society of Chemistry

    J. Carlos Menéndez

  63. Oxidant-free, three-component synthesis of 7-amino-6H-benzo[c]chromen-6-ones under green conditions

    Article • RSC Advances, January 2019, Royal Society of Chemistry

    J. Carlos Menéndez

  64. The Hantzsch Pyrrole Synthesis: Non-conventional Variations and Applications of a Neglected Classical Reaction

    Article • Synthesis, December 2018, Thieme Publishing Group

    J. Carlos Menéndez

  65. Three-Component Synthesis of a Library of m-Terphenyl Derivatives with Embedded β-Aminoester Moieties

    Article • ACS Combinatorial Science, October 2018, American Chemical Society (ACS)

    M. Antonia Martín, J. Carlos Menéndez

  66. Multicomponent Domino Synthesis, Anticancer Activity and Molecular Modeling Simulation of Complex Dispirooxindolopyrrolidines

    Article • Molecules, May 2018, MDPI AG

    J. Carlos Menéndez

  67. Highly functionalized pyrrolidine analogues: stereoselective synthesis and caspase-dependent apoptotic activity

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    J. Carlos Menéndez

  68. Multicomponent mechanochemical synthesis

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    J. Carlos Menéndez

  69. A systematic 1 H- and 13 C-NMR spectral analysis of bicyclo[n.3.1]alkanone systems: Determination of the relative configuration of the stereogenic centres and conformation of the six-membered ring

    Article • Magnetic Resonance in Chemistry, July 2017, Wiley

    J. Carlos Menéndez

  70. One-Pot Synthesis of Functionalized Carbazoles via a CAN-Catalyzed Multicomponent Process Comprising a C–H Activation Step

    Article • The Journal of Organic Chemistry, July 2017, American Chemical Society (ACS)

    J. Carlos Menéndez

  71. Mild and General Synthesis of Pyrrolo[2,1-a]isoquinolines and Related Polyheterocyclic Frameworks from Pyrrole Precursors Derived from a Mechanochemical Multicomponent Reaction

    Article • The Journal of Organic Chemistry, February 2017, American Chemical Society (ACS)

    J. Carlos Menéndez

  72. Synthesis of 6,12-Epiminodibenzo[b,f][1,5]diazocines via an Ytterbium Triflate-Catalyzed, AB2 Three-Component Reaction

    Article • The Journal of Organic Chemistry, October 2016, American Chemical Society (ACS)

    J. Carlos Menéndez

  73. Three-component synthesis of highly functionalized aziridines containing a peptide side chain and their one-step transformation into β-functionalized α-ketoamides

    Article • Beilstein Journal of Organic Chemistry, August 2016, Beilstein Institut

    J. Carlos Menéndez

  74. From Simple Cyclic 1,3-Ketoamides to Complex Spirolactams by Supported Heterogeneous Organocatalysis with PS-BEMP

    Article • Synthesis, July 2016, Thieme Publishing Group

    J. Carlos Menéndez

  75. Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents

    Article • Journal of Medicinal Chemistry, June 2016, American Chemical Society (ACS)

    M. Antonia Martín, J. Carlos Menéndez

  76. One-Pot Access to a Library of Dispiro Oxindole-pyrrolidine/pyrrolothiazole-thiochromane Hybrids via Three-Component 1,3-Dipolar Cycloaddition Reactions

    Article • ACS Combinatorial Science, April 2016, American Chemical Society (ACS)

    J. Carlos Menéndez

  77. Three-Component Synthesis of Pyrrole-Related Nitrogen Heterocycles by a Hantzsch-Type Process: Comparison between Conventional and High-Speed Vibration Milling Conditions

    Article • Asian Journal of Organic Chemistry, March 2016, Wiley

    J. Carlos Menéndez

  78. A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid

    Article • Molecules, January 2016, MDPI AG

    J. Carlos Menéndez

  79. ChemInform Abstract: Dipolar Cycloaddition-Based Multicomponent Reactions in Ionic Liquids: A Green, Fully Stereoselective Synthesis of Novel Polycyclic Cage Systems with the Generation of Two New Azaheterocyclic Rings.

    Article • ChemInform, January 2016, Wiley

    J. Carlos Menéndez

  80. ChemInform Abstract: Expedient, Catalyst-Free, Three-Component Synthesis of Fused Tetrahydropyridines in Water.

    Article • ChemInform, January 2016, Wiley

    J. Carlos Menéndez

  81. Efficient synthesis of 2-acylquinolines based on an aza-vinylogous Povarov reaction

    Article • Organic Chemistry Frontiers, January 2016, Royal Society of Chemistry

    J. Carlos Menéndez

  82. Three-component access to 2-pyrrolin-5-ones and their use in target-oriented and diversity-oriented synthesis

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    J. Carlos Menéndez

  83. Synthesis of 5,6-Dihydrodibenzo[b,h][1,6]naphthyridines via Copper Bromide Catalyzed Intramolecular [4 + 2] Hetero-Diels–Alder Reactions

    Article • The Journal of Organic Chemistry, December 2015, American Chemical Society (ACS)

    J. Carlos Menéndez

  84. Straightforward synthesis of pyrrolo[3,4-b]quinolines through intramolecular Povarov reactions

    Article • Tetrahedron Letters, December 2015, Elsevier

    J. Carlos Menéndez

  85. ChemInform Abstract: An Efficient Synthesis of N-Substituted 3-Nitrothiophen-2-amines.

    Article • ChemInform, November 2015, Wiley

    J. Carlos Menéndez

  86. ChemInform Abstract: Highly Efficient Regioselective Synthesis of Pyrroles via a Tandem Enamine Formation-Michael Addition-Cyclization Sequence under Catalyst- and Solvent-Free Conditions.

    Article • ChemInform, October 2015, Wiley

    J. Carlos Menéndez

  87. An efficient synthesis of N-substituted 3-nitrothiophen-2-amines

    Article • Beilstein Journal of Organic Chemistry, September 2015, Beilstein Institut

    J. Carlos Menéndez

  88. An Expedient Regio- and Diastereoselective Synthesis of Hybrid Frameworks with Embedded Spiro[9,10]dihydroanthracene [9,3′]-pyrrolidine and Spiro[oxindole-3,2′-pyrrolidine] Motifs via an Ionic Liquid-Mediated Multicomponent Reaction

    Article • Molecules, September 2015, MDPI AG

    J. Carlos Menéndez

  89. ChemInform Abstract: Palladium(II)-Catalyzed Intramolecular Carboxypalladation-Olefin Insertion Cascade: Direct Access to Indeno[1,2-b]furan-2-ones.

    Article • ChemInform, August 2015, Wiley

    J. Carlos Menéndez

  90. Dipolar Cycloaddition-Based Multicomponent Reactions in Ionic Liquids: A Green, Fully Stereoselective Synthesis of Novel Polycyclic Cage Systems with the Generation of Two New Azaheterocyclic Rings

    Article • Synthesis, July 2015, Thieme Publishing Group

    J. Carlos Menéndez

  91. ChemInform Abstract: Lewis Acid-Catalyzed Generation of C-C and C-N Bonds on π-Deficient Heterocyclic Substrates.

    Article • ChemInform, May 2015, Wiley

    J. Carlos Menéndez

  92. Six-Membered Heterocycles

    Article • April 2015, Wiley

    J. Carlos Menéndez

  93. ChemInform Abstract: One-Pot α-Amidosulfone-Mediated Variation of the Pictet-Spengler Tetrahydroisoquinoline Synthesis, Suitable for Amide-Type Substrates.

    Article • ChemInform, March 2015, Wiley

    J. Carlos Menéndez

  94. ChemInform Abstract: A Heavy Metal- and Oxidant-Free, One-Pot Synthesis of Pyridines and Fused Pyridines Based on a Lewis Acid-Catalyzed Multicomponent Reaction.

    Article • ChemInform, February 2015, Wiley

    J. Carlos Menéndez

  95. Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience

    Article • Chemical Society Reviews, January 2015, Royal Society of Chemistry

    J. Carlos Menéndez, M. Antonia Martín

  96. Palladium(ii)-catalyzed intramolecular carboxypalladation–olefin insertion cascade: direct access to indeno[1,2-b]furan-2-ones

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    J. Carlos Menéndez

  97. Highly efficient regioselective synthesis of pyrroles via a tandem enamine formation–Michael addition–cyclization sequence under catalyst- and solvent-free conditions

    Article • Green Chemistry, January 2015, Royal Society of Chemistry

    J. Carlos Menéndez

  98. Cancer Chemoprevention

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  99. Preface

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  100. DNA Alkylating Agents

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  101. Biological Therapy of Cancer

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  102. Anticancer Drugs Targeting Tubulin and Microtubules

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  103. Drug Targeting in Anticancer Chemotherapy

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  104. Anticancer Drugs Acting via Radical Species

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  105. Anticancer Drugs That Modulate Hormone Action

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  106. Epigenetic Therapy of Cancer

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  107. General Aspects of Cancer Chemotherapy

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  108. Drugs That Modulate Resistance to Antitumor Agents

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  109. Antimetabolites That Interfere with Nucleic Acid Biosynthesis

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  110. Other Nonbiological Approaches to Targeted Cancer Chemotherapy

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  111. Anticancer Drugs That Interact with the DNA Minor Groove

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  112. Other Anticancer Drugs Targeting DNA and DNA-Associated Enzymes

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  113. Drugs That Inhibit Signaling Pathways for Tumor Cell Growth and Proliferation

    Article • January 2015, Elsevier

    J. Carlos Menéndez

  114. ChemInform Abstract: Fully Diastereoselective Synthesis of Polysubstituted, Functionalized Piperidines and Decahydroquinolines Based on Multicomponent Reactions Catalyzed by Cerium(IV) Ammonium Nitrate.

    Article • ChemInform, January 2015, Wiley

    J. Carlos Menéndez

  115. Expedient, catalyst-free, three-component synthesis of fused tetrahydropyridines in water

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    J. Carlos Menéndez

  116. Lewis Acid-Catalyzed Generation of CC and CN Bonds on π-Deficient Heterocyclic Substrates

    Article • Advanced Synthesis & Catalysis, December 2014, Wiley

    J. Carlos Menéndez

  117. Axial Chirality of 4-Arylpyrazolo[3,4-b]pyridines. Conformational Analysis and Absolute Configuration

    Article • The Journal of Organic Chemistry, November 2014, American Chemical Society (ACS)

    J. Carlos Menéndez

  118. ChemInform Abstract: Recent Advances in the Synthesis of Pyrroles by Multicomponent Reactions

    Article • ChemInform, August 2014, Wiley

    J. Carlos Menéndez

  119. One-Pot α-Amidosulfone-Mediated Variation of the Pictet-Spengler Tetrahydroisoquinoline Synthesis, Suitable for Amide-Type Substrates

    Article • European Journal of Organic Chemistry, August 2014, Wiley

    J. Carlos Menéndez

  120. Fully Diastereoselective Synthesis of Polysubstituted, Functionalized Piperidines and Decahydroquinolines Based on Multicomponent Reactions Catalyzed by Cerium(IV) Ammonium Nitrate

    Article • Chemistry - A European Journal, June 2014, Wiley

    J. Carlos Menéndez

  121. Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation

    Article • Molecules, June 2014, MDPI AG

    J. Carlos Menéndez

  122. B-Ring-Aryl Substituted Luotonin A Analogues with a New Binding Mode to the Topoisomerase 1-DNA Complex Show Enhanced Cytotoxic Activity

    Article • PLOS One, May 2014, PLOS

    M. Antonia Martín, J. Carlos Menéndez

  123. New 5-Unsubstituted Dihydropyridines with Improved CaV1.3 Selectivity as Potential Neuroprotective Agents against Ischemic Injury

    Article • Journal of Medicinal Chemistry, May 2014, American Chemical Society (ACS)

    J. Carlos Menéndez

  124. A catalyst-free multicomponent domino sequence for the diastereoselective synthesis of (E)-3-[2-arylcarbonyl-3-(arylamino)allyl]chromen-4-ones

    Article • Beilstein Journal of Organic Chemistry, February 2014, Beilstein Institut

    J. Carlos Menéndez

  125. ChemInform Abstract: A β-Enaminone-Initiated Multicomponent Domino Reaction for the Synthesis of Indoloquinolizines and Benzoquinolizines from Acyclic Precursors.

    Article • ChemInform, February 2014, Wiley

    J. Carlos Menéndez

  126. Concise synthesis of atorvastatin lactone under high-speed vibration milling conditions

    Article • Organic Chemistry Frontiers, January 2014, Royal Society of Chemistry

    J. Carlos Menéndez

  127. Recent advances in the synthesis of pyrroles by multicomponent reactions

    Article • Chemical Society Reviews, January 2014, Royal Society of Chemistry

    J. Carlos Menéndez

  128. A heavy metal- and oxidant-free, one-pot synthesis of pyridines and fused pyridines based on a Lewis acid-catalyzed multicomponent reaction

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    J. Carlos Menéndez

  129. Synthesis of Heterocycles Through Multicomponent Reactions in Water

    Article • January 2014, Springer Science + Business Media

    J. Carlos Menéndez

  130. ChemInform Abstract: A New CAN-Catalyzed Domino Process Related to the Nenitzescu Reaction: Very Concise Access to Fused ortho-Indolequinones from Simple Precursors.

    Article • ChemInform, October 2013, Wiley

    J. Carlos Menéndez

  131. Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands

    Article • Current Topics in Medicinal Chemistry, October 2013, Bentham Science Publishers

    J. Carlos Menéndez

  132. ChemInform Abstract: Chemodivergent, Multicomponent Domino Reactions in Aqueous Media: L-Proline-Catalyzed Assembly of Densely Functionalized 4H-Pyrano[2,3-c]pyrazoles and Bispyrazolyl Propanoates from Simple, Acyclic Starting Materials.

    Article • ChemInform, August 2013, Wiley

    J. Carlos Menéndez

  133. ChemInform Abstract: Michael Additions in Aqueous Media: “On-Water” and “In-Water” Processes from α-Nitro Ketones and Their Anions.

    Article • ChemInform, August 2013, Wiley

    J. Carlos Menéndez

  134. A β-Enaminone-Initiated Multicomponent Domino Reaction for the Synthesis of Indoloquinolizines and Benzoquinolizines from Acyclic Precursors

    Article • Chemistry - A European Journal, August 2013, Wiley

    J. Carlos Menéndez

  135. A new CAN-catalyzed domino process related to the Nenitzescu reaction: very concise access to fused ortho-indolequinones from simple precursors

    Article • Tetrahedron, July 2013, Elsevier

    J. Carlos Menéndez

  136. Editorial (Hot Topic: Multibond Forming Reactions: A New Frontier in the Synthesis of Heterocycles)

    Article • Current Organic Chemistry, July 2013, Bentham Science Publishers

    J. Carlos Menéndez

  137. L-Proline Catalysed Domino Reactions for the Synthesis of Heterocycles

    Article • Current Organic Chemistry, July 2013, Bentham Science Publishers

    J. Carlos Menéndez

  138. ChemInform Abstract: Diastereoselective, Multicomponent Access to trans-2-Aryl-4-arylamino-1,2,3,4-tetrahydroquinolines via an AA′BC Sequential Four-Component Reaction and Their Application to 2-Arylquinoline Synthesis.

    Article • ChemInform, May 2013, Wiley

    J. Carlos Menéndez

  139. ChemInform Abstract: Microwave-Assisted, Sequential Four-Component Synthesis of Polysubstituted 5,6-Dihydroquinazolinones (IV) from Acyclic Precursors and a Mild, Halogenation-Initiated Method for Their Aromatization [→(V)] under Focused Microwave Irradia

    Article • ChemInform, April 2013, Wiley

    J. Carlos Menéndez

  140. ChemInform Abstract: Three-Component Access to Pyrroles Promoted by the CAN-Silver Nitrate System under High-Speed Vibration Milling Conditions: A Generalization of the Hantzsch Pyrrole Synthesis.

    Article • ChemInform, April 2013, Wiley

    J. Carlos Menéndez

  141. Synthesis of a D Ring-Functionalized Derivative of the Epiwelwistatin Tetracyclic Core

    Article • European Journal of Organic Chemistry, March 2013, Wiley

    J. Carlos Menéndez

  142. Michael Additions in Aqueous Media: “On-Water” and “In-Water” Processes from α-Nitro Ketones and Their Anions

    Article • European Journal of Organic Chemistry, January 2013, Wiley

    J. Carlos Menéndez

  143. ChemInform Abstract: Privileged Scaffolds in Synthesis: 2,5-Piperazinediones as Templates for the Preparation of Structurally Diverse Heterocycles

    Article • ChemInform, January 2013, Wiley

    J. Carlos Menéndez

  144. A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases

    Article • ACS Medicinal Chemistry Letters, January 2013, American Chemical Society (ACS)

    M. Antonia Martín, J. Carlos Menéndez

  145. Three-component access to pyrroles promoted by the CAN–silver nitrate system under high-speed vibration milling conditions: a generalization of the Hantzsch pyrrole synthesis

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    J. Carlos Menéndez

  146. Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    J. Carlos Menéndez, Fernando Padin

  147. Diastereoselective, multicomponent access to trans-2-aryl-4-arylamino-1,2,3,4-tetrahydroquinolines via an AA′BC sequential four-component reaction and their application to 2-arylquinoline synthesis

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    J. Carlos Menéndez

  148. Chemodivergent, multicomponent domino reactions in aqueous media: l-proline-catalyzed assembly of densely functionalized 4H-pyrano[2,3-c]pyrazoles and bispyrazolyl propanoates from simple, acyclic starting materials

    Article • Green Chemistry, January 2013, Royal Society of Chemistry

    J. Carlos Menéndez

  149. Microwave-assisted, sequential four-component synthesis of polysubstituted 5,6-dihydroquinazolinones from acyclic precursors and a mild, halogenation-initiated method for their aromatization under focused microwave irradiation

    Article • Green Chemistry, January 2013, Royal Society of Chemistry

    J. Carlos Menéndez

  150. Solvent- and chromatography-free amination of π-deficient nitrogen heterocycles under microwave irradiation. A fast, efficient and green route to 9-aminoacridines, 4-aminoquinolines and 4-aminoquinazolines and its application to the synthesis of the dr...

    Article • Tetrahedron, January 2013, Elsevier

    J. Carlos Menéndez

  151. ChemInform Abstract: Facile Ionic Liquid-Mediated, Three-Component Sequential Reactions for the Green, Regio- and Diastereoselective Synthesis of Furocoumarins.

    Article • ChemInform, November 2012, Wiley

    J. Carlos Menéndez

  152. One-Pot Access to a Library of Structurally Diverse Nicotinamide Derivatives via a Three-Component Formal Aza [3 + 3] Cycloaddition

    Article • ACS Combinatorial Science, September 2012, American Chemical Society (ACS)

    J. Carlos Menéndez

  153. Fluorescence properties of the anti-tumour alkaloid luotonin A and new synthetic analogues: pH modulation as an approach to their fluorimetric quantitation in biological samples

    Article • Journal of Luminescence, September 2012, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  154. ChemInform Abstract: Aryl Grignard Reagents in Chemodivergent N- and C-Arylations: Concise Access to Two Families of Tetracyclic Fused Carbazoles from 6-Nitroquinolines.

    Article • ChemInform, August 2012, Wiley

    J. Carlos Menéndez

  155. ChemInform Abstract: Domino Reactions in Water: Diastereoselective Synthesis of Densely Functionalized Indolyldihydrofuran Derivatives.

    Article • ChemInform, July 2012, Wiley

    J. Carlos Menéndez

  156. Facile ionic liquid-mediated, three-component sequential reactions for the green, regio- and diastereoselective synthesis of furocoumarins

    Article • Tetrahedron, July 2012, Elsevier

    J. Carlos Menéndez

  157. ChemInform Abstract: Synthesis of Polysubstituted, Functionalized Quinolines Through a Metal-Free Domino Process Involving a C4-C3Functional Group Rearrangement.

    Article • ChemInform, June 2012, Wiley

    J. Carlos Menéndez

  158. Synthesis of Polysubstituted, Functionalized Quinolines through a Metal-Free Domino Process Involving a C 4 –C 3 Functional Group Rearrangement

    Article • Organic Letters, March 2012, American Chemical Society (ACS)

    J. Carlos Menéndez

  159. Aryl Grignard Reagents in Chemodivergent N- and C-Arylations: Concise Access to Two Families of Tetracyclic Fused Carbazoles from 6-Nitroquinolines

    Article • European Journal of Organic Chemistry, March 2012, Wiley

    J. Carlos Menéndez

  160. ChemInform Abstract: L-Proline-Catalyzed Sequential Four-Component “On Water” Protocol for the Synthesis of Structurally Complex Heterocyclic ortho-Quinones.

    Article • ChemInform, March 2012, Wiley

    J. Carlos Menéndez

  161. New Types of Reactivity of α,β‐Unsaturated N , N ‐Dimethylhydrazones: Chemodivergent Diastereoselective Synthesis of Functionalized Tetrahydroquinolines and Hexahydropyrrolo[3,2‐ b ...

    Article • Chemistry - A European Journal, March 2012, Wiley

    J. Carlos Menéndez

  162. ChemInform Abstract: A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation.

    Article • ChemInform, February 2012, Wiley

    J. Carlos Menéndez

  163. ChemInform Abstract: Brief, Efficient and Highly Diastereoselective Synthesis of (.+-.)-Pumiliotoxin C Based on the Generation of an Octahydroquinoline Precursor via a Four-Component Reaction.

    Article • ChemInform, January 2012, Wiley

    J. Carlos Menéndez

  164. ChemInform Abstract: L-Proline-Catalyzed Three-Component Domino Reactions for the Diastereoselective Synthesis of 5,6-Disubstituted 3-Thiomorpholinones.

    Article • ChemInform, January 2012, Wiley

    J. Carlos Menéndez

  165. Privileged scaffolds in synthesis: 2,5-piperazinediones as templates for the preparation of structurally diverse heterocycles

    Article • Chemical Society Reviews, January 2012, Royal Society of Chemistry

    J. Carlos Menéndez

  166. A one-pot sequence for the efficient synthesis of highly functionalized macrocarbocycles or bridged 2,8-dioxabicyclo[3.2.1]octanes from 1-nitrobicyclic compounds

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    J. Carlos Menéndez

  167. Domino reactions in water: diastereoselective synthesis of densely functionalized indolyldihydrofuran derivatives

    Article • Green Chemistry, January 2012, Royal Society of Chemistry

    J. Carlos Menéndez

  168. A systematic study of two complementary protocols allowing the general, mild and efficient deprotection of N-pivaloylindoles

    Article • Tetrahedron, January 2012, Elsevier

    J. Carlos Menéndez

  169. ChemInform Abstract: Advances in the Chemistry of Tetrahydroquinolines

    Article • ChemInform, December 2011, Wiley

    J. Carlos Menéndez

  170. ChemInform Abstract: A Facile, Three-Component Domino Protocol for the Microwave-Assisted Synthesis of Functionalized Naphtho[2,3-b]furan-4,9-diones in Water.

    Article • ChemInform, December 2011, Wiley

    J. Carlos Menéndez

  171. Advances in the Chemistry of Tetrahydroquinolines

    Article • Chemical Reviews, November 2011, American Chemical Society (ACS)

    J. Carlos Menéndez

  172. ChemInform Abstract: Domino Reactions for the Synthesis of Bridged Bicyclic Frameworks: Fast Access to Bicyclo[n.3.1]alkanes

    Article • ChemInform, November 2011, Wiley

    J. Carlos Menéndez

  173. A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation

    Article • Synlett, September 2011, Thieme Publishing Group

    J. Carlos Menéndez

  174. l-Proline-catalysed three-component domino reactions for the diastereoselective synthesis of 5,6-disubstituted 3-thiomorpholinones

    Article • Tetrahedron, September 2011, Elsevier

    J. Carlos Menéndez

  175. Two chemodivergent anionic domino processes from cyclic α-nitroketones and aromatic aldehydes

    Article • Tetrahedron, August 2011, Elsevier

    J. Carlos Menéndez

  176. ChemInform Abstract: A Facile Three-Component [3 + 2]-Cycloaddition/Annulation Domino Protocol for the Regio- and Diastereoselective Synthesis of Novel Penta- and Hexacyclic Cage Systems, Involving the Generation of Two Heterocyclic Rings and Five Contigu

    Article • ChemInform, July 2011, Wiley

    J. Carlos Menéndez

  177. ChemInform Abstract: Synthesis of Benzo- and Naphtho-Fused Bicyclo[n.3.1]alkane Frameworks with a Bridgehead Nitrogen Function by Palladium-Catalyzed Intramolecular α′-Arylation of α-Nitroketones.

    Article • ChemInform, July 2011, Wiley

    J. Carlos Menéndez

  178. Antimycobacterial activity of novel 1,2,4-oxadiazole-pyranopyridine/chromene hybrids generated by chemoselective 1,3-dipolar cycloadditions of nitrile oxides

    Article • Bioorganic & Medicinal Chemistry, June 2011, Elsevier

    J. Carlos Menéndez

  179. ChemInform Abstract: A Three-Component Domino Protocol for the Facile Synthesis of Highly Functionalized Tetrahydroisoquinolines by Creation of Their Benzene Ring.

    Article • ChemInform, May 2011, Wiley

    J. Carlos Menéndez

  180. New four-component reactions in water: a convergent approach to the metal-free synthesis of spiro[indoline/acenaphthylene-3,4′-pyrazolo[3,4-b]pyridine derivatives

    Article • Tetrahedron, May 2011, Elsevier

    J. Carlos Menéndez

  181. A facile three-component [3+2]-cycloaddition/annulation domino protocol for the regio- and diastereoselective synthesis of novel penta- and hexacyclic cage systems, involving the generation of two heterocyclic rings and five contiguous stereocenters

    Article • Tetrahedron, April 2011, Elsevier

    J. Carlos Menéndez

  182. A General, Diastereoselective Synthesis of Highly Functionalized Bicyclo[n.3.1]alkane Systems Based on an Anionic Domino Reaction of α-Nitrocycloalkanones

    Article • European Journal of Organic Chemistry, February 2011, Wiley

    J. Carlos Menéndez

  183. ChemInform Abstract: CAN-Promoted, Diastereoselective Synthesis of Fused 2,3-Dihydrofurans and Their Transformation into Tetrahydroindoles.

    Article • ChemInform, February 2011, Wiley

    J. Carlos Menéndez

  184. A three-component domino protocol for the facile synthesis of highly functionalized tetrahydroisoquinolines by creation of their benzene ring

    Article • Tetrahedron, February 2011, Elsevier

    J. Carlos Menéndez

  185. ChemInform Abstract: Multicomponent Reactions for the Synthesis of Pyrroles

    Article • ChemInform, January 2011, Wiley

    J. Carlos Menéndez

  186. ChemInform Abstract: Three-Component, Diastereoselective Synthesis of Highly Functionalized Indan Derivatives Based on an Anionic Domino Sequence from α-Nitroketones.

    Article • ChemInform, January 2011, Wiley

    J. Carlos Menéndez

  187. Brief, efficient and highly diastereoselective synthesis of (±)-pumiliotoxin C based on the generation of an octahydroquinoline precursor via a four-component reaction

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  188. Domino reactions for the synthesis of bridged bicyclic frameworks: fast access to bicyclo[n.3.1]alkanes

    Article • Chemical Society Reviews, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  189. Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio- and stereoselective 1,3-dipolar cycloaddition

    Article • MedChemComm, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  190. 1,3-Dipolar cycloadditions from tricyclic hemiaminals. Synthesis of the quinocarcin core through catalyst-free generation of azomethine ylides

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  191. Synthesis of benzo- and naphtho-fused bicyclo[n.3.1]alkane frameworks with a bridgehead nitrogen function by palladium-catalyzed intramolecular α′-arylation of α-nitroketones

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  192. Eco-friendly liquid chromatographic separations based on the use of cyclodextrins as mobile phase additives

    Article • Green Chemistry, January 2011, Royal Society of Chemistry

    M. Antonia Martín, J. Carlos Menéndez

  193. l-Proline-catalysed sequential four-component “on water” protocol for the synthesis of structurally complex heterocyclic ortho-quinones

    Article • Green Chemistry, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  194. A facile, three-component domino protocol for the microwave-assisted synthesis of functionalized naphtho[2,3-b]furan-4,9-diones in water

    Article • Green Chemistry, January 2011, Royal Society of Chemistry

    J. Carlos Menéndez

  195. CAN-promoted, diastereoselective synthesis of fused 2,3-dihydrofurans and their transformation into tetrahydroindoles

    Article • Tetrahedron, December 2010, Elsevier

    J. Carlos Menéndez

  196. ChemInform Abstract: Expedient, One-Pot Preparation of Fused Indoles via CAN-Catalyzed Three-Component Domino Sequences and Their Transformation into Polyheterocyclic Compounds Containing Pyrrolo[1,2-a]azepine Fragments.

    Article • ChemInform, November 2010, Wiley

    J. Carlos Menéndez

  197. Environmental Effects on the Fluorescence of the Reaction Products of 2,3-Diphenylquinolizinium Bromide and Amines

    Article • Bulletin des Sociétés Chimiques Belges, September 2010, Wiley

    M. Antonia Martín, J. Carlos Menéndez

  198. Half-Wave Potentials of 1-AZA- and 1,8-Diazaanthraquinones

    Article • Bulletin des Sociétés Chimiques Belges, September 2010, Wiley

    J. Carlos Menéndez

  199. Corrigendum: Cover Picture: Discovery of a Class of Diketopiperazines as Antiprion Compounds (ChemMedChem 8/2010)

    Article • ChemMedChem, August 2010, Wiley

    J. Carlos Menéndez

  200. Three-Component, Diastereoselective Synthesis of Highly Functionalized Indane Derivatives Based on an Anionic Domino Sequence from α-Nitroketones

    Article • Synlett, August 2010, Thieme Publishing Group

    J. Carlos Menéndez

  201. ChemInform Abstract: Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

    Article • ChemInform, July 2010, Wiley

    J. Carlos Menéndez

  202. Cover Picture: Discovery of a Class of Diketopiperazines as Antiprion Compounds (ChemMedChem 8/2010)

    Article • ChemMedChem, July 2010, Wiley

    J. Carlos Menéndez

  203. Synthesis of a Library of 5,6-Unsubstituted 1,4-Dihydropyridines Based on a One-Pot 4CR/Elimination Process and Their Application to the Generation of Structurally Diverse Fused Nitrogen Heterocycles

    Article • Journal of Combinatorial Chemistry, July 2010, American Chemical Society (ACS)

    J. Carlos Menéndez

  204. ChemInform Abstract: Concise Synthesis of Tetrahydro Derivatives of the Pyrido[2,3-b]acridine and Pyrido[3,2-b]acridine Ring Systems.

    Article • ChemInform, June 2010, Wiley

    J. Carlos Menéndez

  205. Discovery of a Class of Diketopiperazines as Antiprion Compounds

    Article • ChemMedChem, June 2010, Wiley

    J. Carlos Menéndez

  206. ChemInform Abstract: Improvements in the Hetero Diels-Alder Reactions of 1-Dimethylamino-1-azadienes in the Presence of an Electrophilic Scavenger Resin.

    Article • ChemInform, June 2010, Wiley

    J. Carlos Menéndez

  207. ChemInform Abstract: Hetero Diels-Alder Reactions of 1-Acetylamino- and 1-Dimethylamino-1-azadienes with Benzoquinones.

    Article • ChemInform, June 2010, Wiley

    J. Carlos Menéndez

  208. ChemInform Abstract: A New Route Toward 4-Substituted Pyrazino[2,1-b]quinazoline-3,6-dione Systems. Total Synthesis of Glyantrypine.

    Article • ChemInform, June 2010, Wiley

    J. Carlos Menéndez

  209. ChemInform Abstract: (o-Trifluoroacetamido)cinnamaldehyde Dimethylhydrazone, a Useful Azadiene in the Hetero Diels-Alder Approach to the Pyrido[2,3,4-kl]acridine System.

    Article • ChemInform, June 2010, Wiley

    J. Carlos Menéndez

  210. ChemInform Abstract: Versatile Synthesis of Malonamic Acid Derivatives from a β-Ketothioester.

    Article • ChemInform, May 2010, Wiley

    J. Carlos Menéndez

  211. ChemInform Abstract: L-Proline-Catalyzed Three-Component Domino [3 + 2 + 1] Annulation for the Regio- and Diastereoselective Synthesis of Highly Substituted Thienothiopyrans Containing Three or Four Stereocenters.

    Article • ChemInform, May 2010, Wiley

    J. Carlos Menéndez

  212. ChemInform Abstract: Efficient Generation of Highly Functionalized Fused Oxazepine Frameworks Based on a CAN-Catalyzed Four-Component Tetrahydropyridine Synthesis/Ring-Closing Metathesis Sequence.

    Article • ChemInform, April 2010, Wiley

    J. Carlos Menéndez

  213. Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

    Article • Chemical Reviews, April 2010, American Chemical Society (ACS)

    J. Carlos Menéndez

  214. ChemInform Abstract: Vinylation of Nitro-Substituted Indoles, Quinolinones, and Anilides with Grignard Reagents.

    Article • ChemInform, February 2010, Wiley

    J. Carlos Menéndez

  215. ChemInform Abstract: A Mild Protocol for the Efficient Synthesis of 5,6-Unsubstituted 1,4-Dihydropyridines.

    Article • ChemInform, January 2010, Wiley

    J. Carlos Menéndez

  216. ChemInform Abstract: Cerium(IV) Ammonium Nitrate Is an Excellent, General Catalyst for the Friedlaender and Friedlaender—Borsche Quinoline Syntheses: Very Efficient Access to the Antitumor Alkaloid Luotonin A.

    Article • ChemInform, January 2010, Wiley

    J. Carlos Menéndez

  217. Concise and very efficient synthesis of the N-methylwelwistatin tetracyclic core based on an anionic domino process

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    J. Carlos Menéndez

  218. Expedient, one-pot preparation of fused indoles via CAN-catalyzed three-component domino sequences and their transformation into polyheterocyclic compounds containing pyrrolo[1,2-a]azepine fragments

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    J. Carlos Menéndez

  219. Multicomponent reactions for the synthesis of pyrroles

    Article • Chemical Society Reviews, January 2010, Royal Society of Chemistry

    J. Carlos Menéndez

  220. ChemInform Abstract: Acid‐Free Synthesis of Carbazoles and Carbazolequinones by Intramolecular Pd‐Catalyzed, Microwave‐Assisted Oxidative Biaryl Coupling Reactions — Efficient Syntheses of Murrayafoline A, 2‐Methoxy‐3‐methylcarbazole, and Glycozolidine.

    Article • ChemInform, December 2009, Wiley

    M. Antonia Martín, J. Carlos Menéndez

  221. l-Proline-Catalyzed Three-Component Domino [3+2+1] Annulation for the Regio- and Diastereoselective Synthesis of Highly Substituted Thienothiopyrans Containing Three or Four Stereocenters

    Article • The Journal of Organic Chemistry, December 2009, American Chemical Society (ACS)

    J. Carlos Menéndez

  222. Mild and High-Yielding Synthesis of β-Keto Esters and β-Ketoamides

    Article • Synthesis, November 2009, Thieme Publishing Group

    J. Carlos Menéndez

  223. Efficient Generation of Highly Functionalized Fused Oxazepine Frameworks Based on a CAN-Catalyzed Four-Component Tetrahydropyridine Synthesis/Ring-Closing Metathesis Sequence

    Article • The Journal of Organic Chemistry, November 2009, American Chemical Society (ACS)

    J. Carlos Menéndez

  224. Vinylation of Nitro-Substituted Indoles, Quinolinones, and Anilides with Grignard Reagents

    Article • Chemistry - A European Journal, September 2009, Wiley

    J. Carlos Menéndez

  225. Acid‐Free Synthesis of Carbazoles and Carbazolequinones by Intramolecular Pd‐Catalyzed, Microwave‐Assisted Oxidative Biaryl Coupling Reactions – Efficient Syntheses of Murrayafoline A, 2‐Methoxy‐3‐methylcarbazole, and Glycozolidine

    Article • European Journal of Organic Chemistry, September 2009, Wiley

    M. Antonia Martín, J. Carlos Menéndez

  226. ChemInform Abstract: A Very Efficient Cerium(IV) Ammonium Nitrate Catalyzed, Four-Component Synthesis of Tetrahydropyridines and Its Application in the Concise Generation of Functionalized Homoquinolizine Frameworks.

    Article • ChemInform, September 2009, Wiley

    J. Carlos Menéndez

  227. A Mild Protocol for the Efficient Synthesis of 5,6-Unsubstituted 1,4-Dihydropyridines

    Article • Synlett, July 2009, Thieme Publishing Group

    J. Carlos Menéndez

  228. ChemInform Abstract: New Synthetic Approaches to Biologically Relevant Heterocyclic Quinones and Quinoneimines

    Article • ChemInform, July 2009, Wiley

    J. Carlos Menéndez

  229. ChemInform Abstract: Convenient, Two-Step Synthesis of 2-Styrylquinolines: An Application of the CAN-Catalyzed Vinylogous Type-II Povarov Reaction.

    Article • ChemInform, July 2009, Wiley

    J. Carlos Menéndez

  230. Cerium(IV) Ammonium Nitrate Is an Excellent, General Catalyst for the Friedländer and Friedländer−Borsche Quinoline Syntheses: Very Efficient Access to the Antitumor Alkaloid Luotonin A

    Article • The Journal of Organic Chemistry, June 2009, American Chemical Society (ACS)

    J. Carlos Menéndez

  231. A Very Efficient Cerium(IV) Ammonium Nitrate Catalyzed, Four-Component Synthesis of Tetrahydropyridines and Its Application in the Concise Generation of Functionalized Homoquinolizine Frameworks

    Article • Chemistry - A European Journal, April 2009, Wiley

    J. Carlos Menéndez

  232. Convenient, two-step synthesis of 2-styrylquinolines: an application of the CAN-catalyzed vinylogous type-II Povarov reaction

    Article • Tetrahedron, March 2009, Elsevier

    J. Carlos Menéndez

  233. ChemInform Abstract: Stereoselective Synthesis of Bicyclo[4.2.1]nonanes - A Temporary-Bridge Approach to Cyclooctanoids.

    Article • ChemInform, February 2009, Wiley

    J. Carlos Menéndez

  234. ChemInform Abstract: Two-Step Stereocontrolled Synthesis of Densely Functionalized Cyclic β-Aminoesters Containing Four Stereocenters, Based on a New Cerium(IV) Ammonium Nitrate Catalyzed Sequential Three-Component Reaction.

    Article • ChemInform, February 2009, Wiley

    J. Carlos Menéndez

  235. Efficient, one-pot transformation of indoles into functionalized oxindole and spirooxindole systems under Swern conditions

    Article • Tetrahedron, February 2009, Elsevier

    J. Carlos Menéndez

  236. Stereoselective Synthesis of Bicyclo[4.2.1]nonanes - a Temporary-Bridge Approach to Cyclooctanoids

    Article • European Journal of Organic Chemistry, October 2008, Wiley

    J. Carlos Menéndez

  237. ChemInform Abstract: Synthesis of Pyrido[3,2-b]carbazolequinones Involving N-Arylation of 5,8-Dimethoxy-6-nitroquinolines by Aryl Grignard Reagents and a New One-Pot, Palladium-Promoted Oxidative Coupling-Oxidative Demethylation Sequence.

    Article • ChemInform, September 2008, Wiley

    J. Carlos Menéndez

  238. Two-Step Stereocontrolled Synthesis of Densely Functionalized Cyclic β-Aminoesters Containing Four Stereocenters, Based on a New Cerium(IV) Ammonium Nitrate Catalyzed Sequential Three-Component Reaction

    Article • Organic Letters, September 2008, American Chemical Society (ACS)

    J. Carlos Menéndez

  239. ChemInform Abstract: New Findings on the Cerium(IV) Ammonium Nitrate Catalyzed Povarov Reaction: Stereoselective Synthesis of 4-Alkoxy-2-aryl-1,2,3,4-tetrahydroquinoline Derivatives.

    Article • ChemInform, August 2008, Wiley

    J. Carlos Menéndez

  240. Trends in the Design and Application of Optical Chemosensors in Pharmaceutical and Biomedical Analysis

    Article • Current Pharmaceutical Analysis, August 2008, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  241. Synthesis of Pyrido[3,2-b]carbazolequinones Involving N-Arylation of 5,8-Dimethoxy-6-nitroquinolines by Aryl Grignard Reagents and a New One-Pot, Palladium-Promoted Oxidative Coupling-Oxidative Demethylation Sequence

    Article • Synlett, May 2008, Thieme Publishing Group

    J. Carlos Menéndez

  242. ChemInform Abstract: Microwave-Assisted, Solvent-Free Synthesis of Several Quinazoline Alkaloid Frameworks.

    Article • ChemInform, March 2008, Wiley

    J. Carlos Menéndez

  243. ChemInform Abstract: One-Pot Synthesis of Highly Functionalized Oxindoles under Swern Oxidation Conditions.

    Article • ChemInform, March 2008, Wiley

    J. Carlos Menéndez

  244. ChemInform Abstract: The Directed Lithiation Route to 2-Amino-3-alkylquinones: Highly Regioselective Introduction of Electrophiles at the C-7 Position of 2(1H)-Quinolinones.

    Article • ChemInform, March 2008, Wiley

    J. Carlos Menéndez

  245. New Findings on the Cerium(IV) Ammonium Nitrate Catalyzed Povarov Reaction: Stereoselective Synthesis of 4-Alkoxy-2-aryl-1,2,3,4-tetrahydro­quinoline Derivatives

    Article • Synthesis, March 2008, Thieme Publishing Group

    J. Carlos Menéndez

  246. DNA Alkylating Agents

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  247. Introduction

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  248. Cancer Chemoprevention

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  249. Antimetabolites

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  250. Preface

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  251. DNA Intercalators and Topoisomerase Inhibitors

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  252. Anticancer Drugs Targeting Tubulin and Microtubules

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  253. Other Approaches to Targeted Therapy

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  254. Drug Targeting in Anticancer Chemotherapy

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  255. Drugs That Modulate Resistance to Antitumor Agents

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  256. Anticancer Drugs That Inhibit Hormone Action

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  257. Alkylating and Non-Alkylating Compounds Interacting with the DNA Minor Groove

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  258. Drugs That Inhibit Signalling Pathways for Tumor Cell Growth and Proliferation

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  259. Anticancer Drugs Acting via Radical Species, Photosensitizers and Photodynamic Therapy of Cancer

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  260. Medicinal Chemistry of Anticancer Drugs

    Article • January 2008, Elsevier

    J. Carlos Menéndez

  261. Convenient Synthesis of Highly Functionalized, 3,4-Disubstituted Indole Building Blocks

    Article • The Open Organic Chemistry Journal, December 2007, Bentham Science Publishers

    J. Carlos Menéndez

  262. Convenient Synthesis of Highly Functionalized, 3,4-Disubstituted Indole Building Blocks

    Article • The Open Organic Chemistry Journal, November 2007, Bentham Science Publishers

    J. Carlos Menéndez

  263. Microwave-Assisted, Solvent-Free Synthesis of Several Quinazoline Alkaloid Frameworks

    Article • Synthesis, November 2007, Thieme Publishing Group

    J. Carlos Menéndez

  264. One-Pot Synthesis of Highly Functionalized Oxindoles under Swern Oxidation Conditions

    Article • Synlett, October 2007, Thieme Publishing Group

    J. Carlos Menéndez

  265. The Directed Lithiation Route to 2-Amino-3-alkylquinones: Highly Regioselective Introduction of Electrophiles at the C-7 Position of 2(1H)-Quinolinones

    Article • Synlett, October 2007, Thieme Publishing Group

    J. Carlos Menéndez

  266. The First Aza Diels—Alder Reaction Involving an α,β-Unsaturated Hydrazone as the Dienophile: Stereoselective Synthesis of C-4 Functionalized 1,2,3,4-Tetrahydroquinolines Containing a Quaternary Stereocenter.

    Article • ChemInform, September 2007, Wiley

    J. Carlos Menéndez

  267. Peptidomimetics in cancer chemotherapy

    Article • Revista de Oncología, September 2007, Springer Science + Business Media

    J. Carlos Menéndez

  268. A New Three-Component Domino Synthesis of 1,4-Dihydropyridines.

    Article • ChemInform, August 2007, Wiley

    J. Carlos Menéndez

  269. CAN-Catalyzed Vinylogous Povarov Reactions: The First Three-Component Synthesis of 2-Functionalized Tetrahydroquinolines from Anilines, Cinnamaldehyde and Vinyl Ethers.

    Article • ChemInform, August 2007, Wiley

    J. Carlos Menéndez

  270. General, Mild and Efficient Synthesis of β-Enaminones Catalyzed by Ceric Ammonium Nitrate.

    Article • ChemInform, August 2007, Wiley

    J. Carlos Menéndez

  271. CAN-Catalyzed Three-Component Reaction Between Anilines and Alkyl Vinyl Ethers: Stereoselective Synthesis of 2-Methyl-1,2,3,4-tetrahydroquinolines and Studies on Their Aromatization.

    Article • ChemInform, May 2007, Wiley

    J. Carlos Menéndez

  272. A new three-component domino synthesis of 1,4-dihydropyridines

    Article • Tetrahedron, May 2007, Elsevier

    J. Carlos Menéndez

  273. CAN-Catalyzed Vinylogous Povarov Reactions: The First Three-Component Synthesis of 2-Functionalized Tetrahydroquinolines from Anilines, ­Cinnamaldehyde and Vinyl Ethers

    Article • Synlett, April 2007, Thieme Publishing Group

    J. Carlos Menéndez

  274. General, Mild and Efficient Synthesis of β-Enaminones Catalyzed by Ceric Ammonium Nitrate

    Article • Synlett, April 2007, Thieme Publishing Group

    J. Carlos Menéndez

  275. Changes in the reactivity of the fluorescent reagents carbazole-9-carbonyl chloride and 9-carbazolylacetic acid in the presence of cyclodextrins

    Article • Journal of inclusion phenomena and molecular recognition in chemistry, February 2007, Springer Science + Business Media

    M. Antonia Martín, J. Carlos Menéndez

  276. Synthesis of Oxygenated Carbazoles by Palladium‐Mediated Oxidative Double C—H Activation of Diarylamines Assisted by Microwave Irradiation.

    Article • ChemInform, January 2007, Wiley

    M. Antonia Martín, J. Carlos Menéndez

  277. The first aza Diels–Alder reaction involving an α,β-unsaturated hydrazone as the dienophile: stereoselective synthesis of C-4 functionalized 1,2,3,4-tetrahydroquinolines containing a quaternary stereocenter

    Article • Organic & Biomolecular Chemistry, January 2007, Royal Society of Chemistry

    J. Carlos Menéndez

  278. CAN-catalyzed three-component reaction between anilines and alkyl vinyl ethers: stereoselective synthesis of 2-methyl-1,2,3,4-tetrahydroquinolines and studies on their aromatization

    Article • Tetrahedron, January 2007, Elsevier

    J. Carlos Menéndez

  279. Structural Studies on Heterocyclic Quinones and Quinonimines

    Article • ChemInform, September 2006, Wiley

    J. Carlos Menéndez

  280. Synthesis of Oxygenated Carbazoles by Palladium-Mediated Oxidative Double C-H Activation of Diarylamines Assisted by Microwave Irradiation

    Article • Synlett, September 2006, Thieme Publishing Group

    M. Antonia Martín, J. Carlos Menéndez

  281. Efficient Synthesis of N -Prenylpyrroloindoline and N -Prenylindole Alkaloids Based on a New Four-Reaction Anionic Domino Process

    Article • Organic Letters, September 2006, American Chemical Society (ACS)

    J. Carlos Menéndez

  282. Multicomponent Reactions

    Article • Synthesis, August 2006, Thieme Publishing Group

    J. Carlos Menéndez

  283. MDR Reversal by Deprenylated Tetracyclic and Hexacyclic Analogues of N-Acetylardeemin: Confirmation of the Ardeemin Pharmacophore

    Article • Letters in Drug Design & Discovery, August 2006, Bentham Science Publishers

    J. Carlos Menéndez

  284. Microwave-Assisted, Solvent-Free Bischler Indole Synthesis.

    Article • ChemInform, May 2006, Wiley

    J. Carlos Menéndez

  285. Microwave-Assisted Synthesis of 2,5-Piperazinediones under Solvent-Free Conditions.

    Article • ChemInform, May 2006, Wiley

    J. Carlos Menéndez

  286. Microwave Assisted Organic Synthesis

    Article • Synthesis, January 2006, Thieme Publishing Group

    J. Carlos Menéndez

  287. Microwave-Assisted, Solvent-Free Bischler Indole Synthesis

    Article • Synlett, January 2006, Thieme Publishing Group

    J. Carlos Menéndez

  288. Solvent-Free, Efficient Synthesis of 2,5-Piperazinediones from Boc-Protected Dipeptide Esters under Microwave Irradiation.

    Article • ChemInform, October 2005, Wiley

    J. Carlos Menéndez

  289. An Efficient Procedure for the Deprotection of N-Pivaloylindoles, Carbazoles and β-Carbolines with LDA.

    Article • ChemInform, May 2005, Wiley

    J. Carlos Menéndez

  290. Environmental effects on the fluorescence behaviour of carbazole derivatization reagents

    Article • Luminescence, May 2005, Wiley

    M. Antonia Martín, J. Carlos Menéndez

  291. Unique Michael Addition-Initiated Domino Reaction for the Stereoselective Synthesis of Functionalized Macrolactones from α-Nitroketones in Water

    Article • Organic Letters, April 2005, American Chemical Society (ACS)

    J. Carlos Menéndez

  292. Microwave-Assisted Synthesis of 2,5-Piperazinediones under Solvent-Free Conditions

    Article • Synthesis, January 2005, Thieme Publishing Group

    J. Carlos Menéndez

  293. An Efficient Procedure for the Deprotection of N -Pivaloylindoles, Carbazoles and β-Carbolines with LDA

    Article • Synlett, January 2005, Thieme Publishing Group

    J. Carlos Menéndez

  294. Solvent-Free, Efficient Synthesis of 2,5-Piperazinediones from Boc-Protected Dipeptide Esters under Microwave Irradiation

    Article • Synlett, January 2005, Thieme Publishing Group

    J. Carlos Menéndez

  295. Synthetic Studies on N-Methylwelwitindolinone C Isothiocyanate (Welwistatin) and Related Substructures

    Article • ChemInform, December 2004, Wiley

    J. Carlos Menéndez

  296. Stereoselective Synthesis of Bicyclo[4.2.1]nonane Skeletons by Ring-Closing Metathesis: A New Versatile Methodology for the Efficient Assembly of Functionalized Cyclooctanoids.

    Article • ChemInform, December 2004, Wiley

    J. Carlos Menéndez

  297. Synthesis and Structure—Activity Relationships of 1,5-Diazaanthraquinones as Antitumor Compounds.

    Article • ChemInform, December 2004, Wiley

    J. Carlos Menéndez

  298. Synthesis and biological evaluation of new 1,5-diazaanthraquinones with cytotoxic activity

    Article • Bioorganic & Medicinal Chemistry, December 2004, Elsevier

    J. Carlos Menéndez

  299. Solvent-Free Cyclocondensation of Lactim Ethers with Anthranilic Acid under Microwave Irradiation.

    Article • ChemInform, August 2004, Wiley

    J. Carlos Menéndez

  300. Stereoselective Synthesis of Bicyclo[4.2.1]nonane Skeletons by Ring-Closing Metathesis:  A New Versatile Methodology for the Efficient Assembly of Functionalized Cyclooctanoids

    Article • Organic Letters, August 2004, American Chemical Society (ACS)

    J. Carlos Menéndez

  301. Synthesis and structure–activity relationships of 1,5-diazaanthraquinones as antitumour compounds

    Article • Bioorganic & Medicinal Chemistry Letters, August 2004, Elsevier

    J. Carlos Menéndez

  302. Practical and User-Friendly Procedure for Michael Reactions of α-Nitroketones in Water.

    Article • ChemInform, March 2004, Wiley

    J. Carlos Menéndez

  303. Brief Total Synthesis of the Cell Cycle Inhibitor Tryprostatin B (I) and Related Preparation of Its Alanine Analogue (II).

    Article • ChemInform, February 2004, Wiley

    J. Carlos Menéndez

  304. Solvent-Free Cyclocondensation of Lactim Ethers with Anthranilic Acid under Microwave Irradiation

    Article • Synlett, January 2004, Thieme Publishing Group

    J. Carlos Menéndez

  305. Synthetic Studies on N-Methylwelwitindolinone C Isothiocyanate (Welwistatin) and Related Substructures

    Article • Current Organic Synthesis, January 2004, Bentham Science Publishers

    J. Carlos Menéndez

  306. Regioselective Diels-Alder Reactions of 3-Vinylindoles with Quinones

    Article • Letters in Organic Chemistry, January 2004, Bentham Science Publishers

    J. Carlos Menéndez

  307. Efficient Synthesis of the Pyrido[2,3,4-kl]acridin-4-one System Common to Several Cytotoxic Marine Alkaloids.

    Article • ChemInform, November 2003, Wiley

    J. Carlos Menéndez

  308. Brief Total Synthesis of the Cell Cycle Inhibitor Tryprostatin B and Related Preparation of Its Alanine Analogue

    Article • The Journal of Organic Chemistry, September 2003, American Chemical Society (ACS)

    J. Carlos Menéndez

  309. Regioselective Diels—Alder Reactions of 3-Indolylquinones.

    Article • ChemInform, August 2003, Wiley

    J. Carlos Menéndez

  310. Detection and characterization of cyclodextrin complexes with β-carboline derivatives by spectroscopic techniques

    Article • Journal of Pharmaceutical and Biomedical Analysis, August 2003, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  311. Efficient synthesis of the pyrido[2,3,4-kl]acridin-4-one system common to several cytotoxic marine alkaloids

    Article • Tetrahedron Letters, August 2003, Elsevier

    J. Carlos Menéndez

  312. Chemistry of Pyrazino[2,1-b]quinazoline-3,6-diones

    Article • ChemInform, July 2003, Wiley

    J. Carlos Menéndez

  313. Regioselective Diels–Alder reactions of 3-indolylquinones

    Article • Tetrahedron, April 2003, Elsevier

    J. Carlos Menéndez

  314. Efficient, Multigram-Scale Synthesis of Three 2,5-Dihalobenzoquinones

    Article • ChemInform, January 2003, Wiley

    J. Carlos Menéndez

  315. Practical and User-Friendly Procedure for Michael Reactions of α-Nitro­ketones in Water

    Article • Synlett, January 2003, Thieme Publishing Group

    J. Carlos Menéndez

  316. Chemistry of Pyrazino[2,1-b]quinazoline-3,6-diones

    Article • Current Organic Chemistry, January 2003, Bentham Science Publishers

    J. Carlos Menéndez

  317. Differentiating geometrical isomers of retinoids and controlling their photo-isomerization by complexation with cyclodextrins

    Article • Analytica Chimica Acta, September 2002, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  318. EFFICIENT, MULTIGRAM-SCALE SYNTHESIS OF THREE 2,5-DIHALOBENZOQUINONES

    Article • Synthetic Communications, January 2002, Taylor & Francis

    J. Carlos Menéndez

  319. Inhibitors of Multidrug Resistance to Antitumor Agents (MDR)

    Article • Current Medicinal Chemistry, January 2002, Bentham Science Publishers

    J. Carlos Menéndez

  320. One-pot assembly of large heterocyclic quinones through three-component reactions

    Article • Tetrahedron Letters, November 2001, Elsevier

    J. Carlos Menéndez

  321. Versatile synthesis of malonamic acid derivatives from a β-ketothioester

    Article • Tetrahedron Letters, July 2001, Elsevier

    J. Carlos Menéndez

  322. A C-Ring Regioisomer of the Marine Alkaloid Meridine Exhibits Selective In Vitro Cytotoxicity for Solid Tumours

    Article • Bioorganic & Medicinal Chemistry, July 2001, Elsevier

    J. Carlos Menéndez

  323. Hydantoin and Its Derivatives

    Article • December 2000, Wiley

    J. Carlos Menéndez

  324. ChemInform Abstract: Concise Preparation of 1,8-Diazaanthracene-2,7,9,10-tetraones. Two Alternative Syntheses of the Natural Antifolate Diazaquinomycin A.

    Article • ChemInform, October 2000, Wiley

    J. Carlos Menéndez

  325. Concise Preparation of 1,8-Diazaanthracene-2,7,9,10-Tetraones. Two Alternative Syntheses of the Natural Antifolate Diazaquinomycin A

    Article • Tetrahedron, June 2000, Elsevier

    J. Carlos Menéndez

  326. Hetero Diels–Alder Reactions of 1-Acetylamino- and 1-Dimethylamino-1-azadienes with Benzoquinones

    Article • Tetrahedron, March 2000, Elsevier

    J. Carlos Menéndez

  327. A New Route toward 4-Substituted Pyrazino[2,1-b]quinazoline-3,6-dione Systems. Total Synthesis of Glyantrypine

    Article • The Journal of Organic Chemistry, February 2000, American Chemical Society (ACS)

    J. Carlos Menéndez

  328. Improvements in the Hetero Diels-Alder Reactions of 1-Dimethylamino-1-azadienes in the Presence of an Electrophilic Scavenger Resin

    Article • Synlett, February 2000, Thieme Publishing Group

    J. Carlos Menéndez

  329. Synthesis of a Seco Analogue of Ardeemin

    Article • Heterocycles, January 2000, Japan Institute of Heterocyclic Chemistry

    J. Carlos Menéndez

  330. ELECTROCHEMICAL EVIDENCE FOR OXO-ENOL TAUTOMERISM OF AZAANTHRACENE-4,9,10-TRIONES

    Article • Heterocyclic Communications, January 2000, De Gruyter

    J. Carlos Menéndez

  331. Steric and stereochemical effects on the free-radical bromination of tetracyclic and hexacyclic fragments of the MDR inhibitor N-acetylardeemin

    Article • Tetrahedron, December 1999, Elsevier

    J. Carlos Menéndez

  332. Concise synthesis of tetrahydro derivatives of the pyrido[2,3-b]acridine and pyrido[3,2-b]acridine ring systems

    Article • Tetrahedron, October 1999, Elsevier

    J. Carlos Menéndez

  333. Synthesis of 1,2,3,4-tetrahydroascididemin

    Article • Tetrahedron Letters, May 1999, Elsevier

    J. Carlos Menéndez

  334. Quantitative determination of dimethicone in commercial tablets and capsules by Fourier transform infrared spectroscopy and antifoaming activity test

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 1999, Elsevier

    J. Carlos Menéndez

  335. Comparative study of synthetic approaches to 1-arylmethylenepyrazino[2,1-b]quinazoline-3,6-diones

    Article • Tetrahedron, October 1998, Elsevier

    J. Carlos Menéndez

  336. On the fate of the tryptophan stereocenter during the synthesis of hexacyclic analogues of N-acetylardeemin

    Article • Tetrahedron Asymmetry, September 1998, Elsevier

    J. Carlos Menéndez

  337. Stereochemical issues related to the synthesis and reactivity of pyrazino[2′,1′-5,1]pyrrolo[2,3-b]indole-1,4-diones

    Article • Tetrahedron Asymmetry, March 1998, Elsevier

    J. Carlos Menéndez

  338. A General Synthesis of Quinoline-2,5,8(1H)-triones via Acylation of 2,5-Dimethoxyaniline with S-tert-Butyl Thioacetates by Application of the Knorr Cyclization

    Article • Synthesis, February 1998, Thieme Publishing Group

    J. Carlos Menéndez

  339. Total synthesis of diazaquinomycin A

    Article • Tetrahedron Letters, February 1998, Elsevier

    J. Carlos Menéndez

  340. Hetero Diels-Alder reactions of 4,5,8(1H)-quinolinetriones

    Article • Tetrahedron, August 1997, Elsevier

    J. Carlos Menéndez

  341. A very efficient synthesis of 1,8-diazaanthraquinones

    Article • Tetrahedron Letters, June 1997, Elsevier

    J. Carlos Menéndez

  342. 1,2-Dihydroquinolin-2-one (carbostyril) anions as bidentate nucleophiles in their reactions with aryllead triacetates: synthesis of 1-aryl- and 3-aryl-tetrahydroquinoline-2,5,8-triones

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    J. Carlos Menéndez

  343. Silica gel-supported hetero Diels-Alder reactions of quinolinetriones

    Article • Tetrahedron Letters, September 1996, Elsevier

    J. Carlos Menéndez

  344. Analytical applications of retinoid—cyclodextrin inclusion complexes

    Article • Journal of Pharmaceutical and Biomedical Analysis, June 1996, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  345. New findings in hetero Diels-Alder reactions of quinolinetriones

    Article • Tetrahedron, April 1996, Elsevier

    J. Carlos Menéndez

  346. Bicyclic 6-6 Systems with One Ring Junction Nitrogen Atom: No Extra Heteroatom

    Article • January 1996, Elsevier

    J. Carlos Menéndez

  347. New Synthetic Applications of Aryllead Triacetates. N-Arylation of Amides

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    J. Carlos Menéndez

  348. New synthetic applications of aryllead triacetates. N-arylation of azoles.

    Article • The Journal of Organic Chemistry, September 1995, American Chemical Society (ACS)

    J. Carlos Menéndez

  349. 1-Acylamino-1-azadienes as an alternative to 1-dimethylamino-1-azadienes in the preparation of 1,8-diazaanthracene-2,9,10-triones.

    Article • Tetrahedron, June 1995, Elsevier

    J. Carlos Menéndez

  350. Solvent effects on the fluorescent emission of some new benzimidazole derivatives

    Article • Analytica Chimica Acta, February 1995, Elsevier

    M. Antonia Martín, J. Carlos Menéndez

  351. Regioselectivity of the Diels-Alder reactions of 2,5,8(1H)-quinolinetriones

    Article • Tetrahedron, January 1994, Elsevier

    J. Carlos Menéndez

  352. Ultrasound assisted Diels-Alder reactions of 1-azadienes with “normal” electronic demand.

    Article • Tetrahedron, January 1994, Elsevier

    J. Carlos Menéndez

  353. Re-examination of the Synthesis of 3,5-Dimethoxy-2-nitrobenzaldehyde

    Article • Synthetic Communications, May 1993, Taylor & Francis

    J. Carlos Menéndez

  354. New findings on the Vilsmeier-Haack approach to quinoline derivatives

    Article • Tetrahedron, January 1993, Elsevier

    J. Carlos Menéndez

  355. Amide N-arylation with p-tolyllead triacetate

    Article • Tetrahedron Letters, November 1992, Elsevier

    J. Carlos Menéndez

  356. An Improved Multigram-Scale Preparation ofS-TertButyl Acetothioacetate

    Article • Synthetic Communications, August 1992, Taylor & Francis

    J. Carlos Menéndez

  357. N-arylation of azoles and their benzo derivatives by p-tolyllead triacetate

    Article • Tetrahedron Letters, January 1992, Elsevier

    J. Carlos Menéndez

  358. Synthesis, anticonvulsant and antihypertensive activity of diastereomeric 9,10-dimethoxy-1,3,4,6,7,11b-hexahydrospiro-[benzo[a]quinolizin-2,4′-imidazolidine]-2′,5′-diones

    Article • European Journal of Medicinal Chemistry, January 1992, Elsevier

    J. Carlos Menéndez

  359. Total Synthesis of the Carboxylic Acid lonophore Antibiotic CP-61,405 (Routiennocin): Preparation of the Inherent Spiroketal Unit via a Reverse Coupling Process

    Article • Synlett, January 1992, Thieme Publishing Group

    J. Carlos Menéndez

  360. Total synthesis of the ionophore antibiotic CP-61,405 (routiennocin)

    Article • Tetrahedron, January 1992, Elsevier

    J. Carlos Menéndez

  361. Synthesis of 1′-substituted and 1′,3′-disubstituted (±)-2R*, 11bS*-9,10-Dimethoxy-1,3,4,6,7,11 b-Hexahydrospiro-[benzo[a]quinolizin-2,5′-imidazolidine]-2′,4′-diones

    Article • Journal of Heterocyclic Chemistry, June 1991, Wiley

    J. Carlos Menéndez

  362. Study of the Reaction Between Cyanohydrins and Chlorosulfonyl Isocyanate. A New, Efficient Method for the One-Pot Synthesis of 2,4-Oxazolidinediones

    Article • Synthesis, January 1991, Thieme Publishing Group

    J. Carlos Menéndez

  363. The application of ultrasound to the strecker synthesis on 9,10-dimethoxy-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one

    Article • Tetrahedron Letters, January 1986, Elsevier

    J. Carlos Menéndez

  364. Chemistry of the Welwitindolinones

    Article • Springer Science + Business Media

    J. Carlos Menéndez