What is it about?
Menière's disease in a disabling inne ear disease which has been first describen in 1861. It's pathophysiology is still not understood and there is no evidence based treatment except destroying the function of the vestibular organ, which is often accompanied by hearimg loss.
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Why is it important?
This hypothesis describes a unique pathophysiology of Menière's disease. It explains the attacks of simulatenous cochlear and vestibular symptoms, development of endolymphatic hydrops as well as the close connection of Menière's disease and Migraine.
Perspectives
If proven correct, it will soon enable new ways of therapy for this debilitating disease of the inner ear, which seems very important, since there is sofar no evidence based therapy beside destructive methods.
Stefan Hegemann
Read the Original
This page is a summary of: Menière’s disease caused by CGRP - A new hypothesis explaining etiology and pathophysiology. Redirecting Menière’s syndrome to Menière’s disease, Journal of Vestibular Research, July 2021, IOS Press,
DOI: 10.3233/ves-200716.
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