What is it about?

This review examines evidence for signaling from skeletal muscle to brain in response to exercise and associated components (cell stress, energy demand, etc) and the consequent impact on brain aging, neurodegeneration, and the regulation of brain-dependent behaviors.

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Why is it important?

Understanding signaling from muscle to the brain may provide therapeutic opportunities for preserving brain function during aging.

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This page is a summary of: Muscle-to-Brain Signaling Via Myokines and Myometabolites, Brain Plasticity, October 2022, IOS Press,
DOI: 10.3233/bpl-210133.
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