Efficacy of Bridelia ferruginea stem bark in reducing Iron(II) induced oxidative stress

What is it about?

The antioxidant potential of Bridelia ferruginea, which is a widely used medicinal plant in Nigeria, sub-tropical Africa and parts of Asia was investigated using thiobarbituric acid reactive species (TBARS) assay. The aqueous extract of Bridelia ferruginea stem bark used in this study showed inhibition against the formation of thiobarbituric acid reactive species (TBARS) induced by Iron (II) sulphate in the liver and brain tissue homogenates of the locally bred male and female albino- Wistar rats used. The extract was discovered to have different antioxidant potentials in a manner that was concentration dependent. The result therefore suggests the medicinal benefit of Bridelia ferruginea in the treatment of various diseases induced by oxidative stress due to its ability to act as antioxidant.

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Why is it important?

This work gives an insight into the potency of the plant extract in managing diseases induced by oxidative stress. It also pointed out the fact that herbal medicines, though effective in the management of diseases, are most potent at a well-researched concentration as against the practice of taking it without recourse to concentration. This will help prevent the age-long abuse of herbal medicines.

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