Phytochemical screening and antihyperglycemic activity of Heliotropium indicum whole plant in Streptozotocin induced diabetic rats

  • Journal of Applied Pharmaceutical Science, December 2014, Journal of Applied Pharmaceutical Science
  • DOI: 10.7324/japs.2014.41212

whole plant extract of Heliotropium indum in screenig of antidiabetic activity

What is it about?

When different solvent extracts of HI each at a dose of 500 mg/kg bw were given to diabetic rats, the methanol and aqueous extracts produced significant (P<0.0001) antidiabetic activity.

Why is it important?

Phytochemical screening of various solvent extracts of HI whole plant revealed the presence of alkaloids, steroids, triterpenes, saponins and tannins

Perspectives

Dr. saritha Marella

When methanol active fraction of Heliotropium indicum (MAFHI) was checked for its antidiabetic activity, the fraction at dose of 750 mg/kg bw produced marked antihyperglycemic activity. The antihyperglycemic activity was also exhibited during oral glucose tolerance test (OGTT) with the same dosage of MAFHI.

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http://dx.doi.org/10.7324/japs.2014.41212

The following have contributed to this page: Dr. saritha Marella