What is it about?

This article demonstrated the methods on how a human immortalised corneal epithelial cell line showed similar characteristics to primary limbal stem cells.

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Why is it important?

Understanding more about the immunobiology of limbal stem cells is important to improve the outcome of cellular transplantation. However, the human tissue needed as a supply of limbal stem cells for this research is not readily available. As an alternative, a human telomerase‐immortalized corneal epithelial cell line is demonstrated to be useful for this purpose.


This provides an excellent option to study limbal stem cells without primary cells being readily available.

Bakiah Shaharuddin
Universiti Sains Malaysia

Read the Original

This page is a summary of: A Human Corneal Epithelial Cell Line Model for Limbal Stem Cell Biology and Limbal Immunobiology, Stem Cells Translational Medicine, October 2016, Wiley, DOI: 10.5966/sctm.2016-0175.
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