New Insights on Critical Reagent Optimization for Antidrug Antibody Assays

What is it about?

Conjugated monoclonal antibodies are commonly used as critical reagents for anti-drug antibodies ligand binding assays. Here we developed, characterized and screened a toolset of bioconjugates that provided new insights about the optimization of conjugated critical reagent attributes. This work demonstrates how these conjugation attributes can be used to rationally customize conjugated critical reagents and achieve a better and robust assay.

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