What is it about?

To investigate quality of life (QoL) domains with three forms of urinary diversions, including ileal conduit, MAINZ pouch, and orthotopic ileal neobladder after radical cystectomy in men with muscle-invasive bladder cancer.

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Why is it important?

Various methods are used for urinary diversion after radical cystectomy, including ileal conduits, cutaneous continent urinary diversion, and orthotopic neobladder reconstruction. Types of urinary diversion have a great impact on different aspects of quality of life (QoL), including micturition status, physical, sexual, and psychosocial functioning, day life activities, and distress related to body image. A number of studies have addressed these QoL issues following radical cystectomy with various types of urinary diversions. So far, more than 30 articles have made comparisons of the impact of different types of urinary diversion on patient QoL. A major obstacle is lacking of disease‑specific QoL instrument, which universally compares patients after urinary diversion.


There is a wide disparity in practice in the selection of method for urinary diversion worldwide.[19‑21] The rates of ileal conduit diversion and orthotopic bladder replacement differ significantly from centre to centre ranging from less than 20% to more than 75%, but most European countries favor orthotopic bladder replacements. In the present study, 47.0% of recruited patients underwent ileal conduit urinary diversion. A recent consensus conference of experts under the sponsorship of the WHO and Société international d’Urologie (SIU) on urinary diversion demonstrated a change in the surgeons’ practice, with nearly 50%‑90% of their procedures being bladder substitution. Patient education, describing the pros and cons of the different urinary diversion methods, and active participation of patient in selecting treatment methods appear to be some of the key points to postoperative QoL and satisfaction.

Dr Mohammad Reza Safarinejad
University of Medical Sceices

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This page is a summary of: Quality of life after radical cystectomy for bladder cancer in men with an ileal conduit or continent urinary diversion: A comparative study, Urology Annals, January 2013, Medknow, DOI: 10.4103/0974-7796.115747.
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