What is it about?
This article reviews the outcome of home parenteral nutrition in a large cohort (251 children) over a 14y period. The outcomes studied were weaning off parenteral nutrition, intestinal transplantation and death. The factors associated with different outcomes were studied. The complications of long-term parenteral nutrition were also reviewed, mainly catheter-related bloodstream infections and intestinal-failure associated liver disease.
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Why is it important?
Intestinal failure is a rare disease. Few centers in France and Europe are specialized in the management of long-term parenteral nutrition, its complications and indications of intestinal and/or liver transplantation. This study is one of few that includes a large number of children followed over a long period. Our department has the largest European cohort of children receiving home parenteral nutrition and was the first European center to perform intestinal transplantation in children in 1987.
Perspectives
Having a large cohort of children receiving home parenteral nutrition gives us the opportunity to better manage intestinal failure in children and avoid complications of long-term parenteral nutrition. Several very interesting studies are currently ongoing in our department on the different aspects of intestinal failure.
Dr Elie ABI NADER
Necker Enfants Malades University Hospital, Department of Pediatric Gastroenterology, Hepatology and Nutrition
Read the Original
This page is a summary of: Outcome of home parenteral nutrition in 251 children over a 14-y period: report of a single center, American Journal of Clinical Nutrition, March 2016, American Society for Nutrition,
DOI: 10.3945/ajcn.115.121756.
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