Poly(alkyl methacrylate) Tooth Coatings for Dental Care: Evaluation of the Demineralisation-Protection Benefit Using a Time-Resolved In Vitro Method

Birthe V. Nielsen, Thomas G. Nevell, Eugen Barbu, James R. Smith, Gareth D. Rees, John Tsibouklis
  • Polymers, January 2011, MDPI AG
  • DOI: 10.3390/polym3010314

Method for quantification of tooth demineralisation for testing dental coatings

Photo by John-Mark Smith on Unsplash

Photo by John-Mark Smith on Unsplash

What is it about?

An in vitro method for the time-resolved quantification of acid-mediated tooth demineralisation has been developed and evaluated against non-permanent protective formulations based on a series of poly(alkyl methacrylate)s. Using a thermostatted carousel, dentally relevant substrates consisting of hydroxyapatite discs or sections of bovine teeth have been exposed to aqueous citric acid under controlled conditions, before and after being treated with the polymeric coatings. The dissolution of phosphate was monitored by the determination of 31P by Inductively Coupled Plasma—Mass Spectrometry and by the spectrophotometric phosphovanadomolybdate method. Dose-response plots constructed for both groups of treated substrates have revealed that the coatings significantly reduce erosion rates but are less effective at inhibiting tooth demineralisation than the standard fluoride treatment.

Why is it important?

The approach has enabled an evaluation of the erosion-protection efficiency of polymer coatings.


Dr James R Smith
University of Portsmouth

This paper is open access.

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The following have contributed to this page: Dr James R Smith