What is it about?

This review summarizes the current evidence regarding the role of maternal diet (food, beverages and supplements use) during pregnancy may contribute to the development of leukaemia in the child. A total of 38 studies were included, and the published risk estimates were combined into a meta-analysis.

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Why is it important?

The main findings indicates that eating two or more daily servings of fruits during pregnancy decreases the risk of developing leukaemia (odds ratio = 0.71; 95% CI, 0.59–0.86), whereas coffee intake (two or more cups per day) increases it (odds ratio = 1.45; 95% CI, 1.12–1.89). These findings are useful to encourage a healthy diet during pregnancy.

Perspectives

More studies are needed to clarify these and other lifestyle factors that may modify the risk of developing acute leukaemia in children, and promote prevention strategies.

Jessica Blanco
Unidad Nacional de Oncologia Pediatrica

Read the Original

This page is a summary of: Role of Maternal Diet in the Risk of Childhood Acute Leukemia: A Systematic Review and Meta-Analysis, International Journal of Environmental Research and Public Health, April 2023, MDPI AG,
DOI: 10.3390/ijerph20075428.
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