What is it about?
This review brings together the results of 15 clinical trials that tested Ginkgo biloba extract in people with Alzheimer’s disease or other dementias. Ginkgo is a tree used in traditional medicine for centuries, and its leaves contain compounds with antioxidant and anti-inflammatory properties. The analysis shows mixed results: in most studies, people taking Ginkgo had improvements in memory, daily activities, and behavioral symptoms, while a few trials showed no benefit compared to placebo. The standardized extract EGb 761 was the most studied, with doses ranging from 120 to 240 mg daily. Overall, the findings suggest that Ginkgo may ease symptoms of dementia, although more research is needed to confirm who benefits most and how best to use it.
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Why is it important?
Alzheimer’s disease is one of the greatest health challenges of our time, with limited treatment options. This review highlights that a widely available plant extract might improve quality of life for patients, especially when conventional drugs bring limited relief or unwanted side effects. It also points toward sustainable, natural compounds as part of future dementia care strategies.
Perspectives
What I find most compelling is how Ginkgo, a tree that has survived unchanged for millions of years, is now being studied as a possible ally against one of today’s toughest diseases. The results are not perfect, but they open an important conversation about combining modern medicine with natural products. To me, this work reflects the need to keep exploring every possible path—traditional and innovative—to help people live better with dementia.
Dr. Rosa Direito
Universidade de Lisboa
Read the Original
This page is a summary of: Ginkgo biloba: A Leaf of Hope in the Fight against Alzheimer’s Dementia: Clinical Trial Systematic Review, Antioxidants, May 2024, MDPI AG,
DOI: 10.3390/antiox13060651.
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