What is it about?
T2-MRI showed dilated perivascular spaces in early middle-aged healthy people. The incidence of perivascular spaces increased associated with increasing age. The logistic regression analysis revealed that dilated perivascular spaces on MRI were closely associated with age, hypertension, and the estimated glomerular filtration ratio.
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Why is it important?
Dilated perivascular spaces are regarded as a MRI marker of small vessel disease and amyloid angiopathy. This study revealed that development of dilated perivascular spaces onMI started in the middle-aged healthy people.
Perspectives
Dilated perivascular spaces on MRI can be a marker that both of stroke and Alzheimer's dementia could have a same pathogenesis in the middle age of life.
Masatsune Ishikawa
Rakuwa Villa Ilios
Read the Original
This page is a summary of: Dilated Perivascular Spaces in the Centrum Semiovale Begin to Develop in Middle Age, Journal of Alzheimer s Disease, January 2018, IOS Press,
DOI: 10.3233/jad-170755.
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