What is it about?
we focus on the use of bioactive polymers for drug delivery system, with a particular in the utility of DNA-based nanocarriers and cell-penetrating peptides (CCPs)-based nanocarriers to provide precision control for drug targeting or stimuli responsive systems.
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Why is it important?
Development of smart and functional polymeric carriers, which enable controlled or timed release of a bioactive material, thereby providing a better dosing pattern and minimizing side effects, becomes a new requirement in the field of drug delivery.
Perspectives
we introduced two bioactive polymer nanocarriers and their application in drug delivery system. Although, targeted drug delivery systems mediated by DNA and CPPs have made some progress in biomedical application, they have faced significant challenges to get through approval processes and clinical trials. Thus, further researches are needed to decisively overcome these obstacles for future clinical applications of drug delivery system.
Weiqun Tian
Department of Biomedical Engineering, School of Basic Medical Science, Wuhan University
Read the Original
This page is a summary of: Advance of DNA and CCPs-based nanocarriers in drug delivery systems, Bio-Medical Materials and Engineering, March 2017, IOS Press,
DOI: 10.3233/bme-171648.
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