What is it about?

Subthalamic nucleus deep brain stimulation (STN-DBS) is a treatment for people with advanced Parkinson's disease that is effective at improving motor symptoms. However, we demonstrate here that during a memory-guided reaching task STN-DBS can improve certain aspects of movement (such as velocity and amplitude) while simultaneously impairing other aspects of movement (reaching accuracy).

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Why is it important?

These findings help infer the underlying neurophysiological processes affected by STN-DBS. Furthermore, utilizing memory-guided reaching tasks to test the effectiveness of STN-DBS under different stimulation parameters may pave the way for establishing the most effective STN-DBS parameters that optimize all aspects of movement control.

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This page is a summary of: The Effects of Subthalamic Nucleus Deep Brain Stimulation and Retention Delay on Memory-Guided Reaching Performance in People with Parkinson’s Disease, Journal of Parkinson s Disease, September 2023, IOS Press,
DOI: 10.3233/jpd-225041.
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