What is it about?

Although choroidal thickness is considered to be potentially useful for early diagnosis or as a follow-up tool, the role of the choroidal vasculature in the pathogenesis of AD is unclear.To fill this gap in knowledge, this study was to investigate the association between retinal choroidal properties and the pathology of AD by determining choroidal thickness, hippocampus volume, cognitive functions, and plasma BACE1 activity.

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Why is it important?

Our findings showed a general tendency of choroid thinning as the cognitive function declined. Although choroidal thickness was not a potential indicator for early stage AD, it was valuable in monitoring AD progression.


I hope that this article will bring more attention to Alzheimer's disease, stimulate enthusiasm for Alzheimer's disease research, and ultimately benefit more patients.

Mo Li

Read the Original

This page is a summary of: Relationship Between Alzheimer’s Disease and Retinal Choroidal Thickness: A Cross-Sectional Study, Journal of Alzheimer s Disease, March 2021, IOS Press, DOI: 10.3233/jad-201142.
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