Relationship between SIBO and other bowel diseases and a common eating pattern for them. Part III

What is it about?

Introduction and Objective: Disorders related to the brain-gut and gum-gut axes exhibit complex, often bidirectional interactions. The resulting imbalances in intestinal microflora can be managed through appropriately tailored dietary therapy. This study aims to examine the relationship between small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS) as well as non-specific inflammatory bowel diseases (IBD) and to assess dietary recommendations. Review Methods: A literature review was conducted using PubMed, Google Scholar, and Web of Science. The findings were synthesized through a non-systematic review. State of Knowledge: Clinically, SIBO is most commonly associated with IBS, as both share symptoms such as abdominal pain, bloating, and diarrhea, as well as similar neuropsychological issues. IBS and IBD also have overlapping features, leading to the term "IBS in IBD." Regarding diet therapy, a low-FODMAP diet is often recommended, along with probiotic therapy to restore microbiological balance. Summary: Recent studies highlight a strong link between SIBO and IBD, particularly in Crohn’s disease patients compared to those with ulcerative colitis. Effective treatment and disease prevention require interdisciplinary collaboration, integrating pharmacotherapy, psychotherapy, probiotic therapy, and diet therapy in a personalized manner.

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Why is it important?

Studies indicate a link between SIBO and IBD, with SIBO being more common in Crohn’s disease than in ulcerative colitis. Effective treatment and relapse prevention require interdisciplinary cooperation and an individualized approach combining pharmacotherapy, psychotherapy, probiotic therapy, and diet therapy.