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In a genetic study conducted using publicly available data from 921,908 participants and individual-level data from 92,532 participants from 14 observational studies, we found consistent evidence that LDLc lowering was associated with an increased risk of type 2 diabetes, and that body mass index partially mediated this effect.
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This page is a summary of: Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol, Diabetes Care, November 2021, American Diabetes Association,
DOI: 10.2337/dc21-1284.
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