What is it about?
Precision nutrition has great potential to offer multidimensional and dynamic nutrition recommendations. We have shown that a designer protein-deprived diet enriched in free essential amino acids can i) promote the brown fat thermogenic program and fatty acid oxidation, ii) stimulate uncoupling protein 1 (UCP1)-independent respiration in subcutaneous white fat, iii) change the gut microbiota composition, and iv) prevent and reverse obesity and dysregulated glucose homeostasis in multiple mouse models, prolonging the healthy lifespan.
Photo by Ella Olsson on Unsplash
Why is it important?
Our results suggest that brown and white fat may be targets of specific amino acids to control UCP1-dependent and -independent thermogenesis, thereby contributing to the improvement of metabolic health.
Read the Original
This page is a summary of: Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis, Diabetes, August 2020, American Diabetes Association, DOI: 10.2337/db20-0489.
You can read the full text:
The following have contributed to this page