Atypical Chronic Myeloid Leukemia: A Rare Entity with Management Challenges

What is it about?

Atypical chronic myeloid leukemia (aCML) is a rare type of leukemia. aCML is a different entity from chronic myeloid leukemia, and lacks specific genetic or molecular features. It can be difficult to diagnose and treat, and the median survival of patients with aCML is 1-2 years. Bone marrow transplant may be the only curative option. Ruxolitinib and dasatinib are emerging as potential therapeutic options.

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