What is it about?
MEIS family of proteins are found to be important regulators of homeostasis. Studies in the last decade have shown that Meis1 has crucial roles in cardiac regeneration, stem cell function, and tumorigenesis. MEIS proteins are associated with limited cardiac regeneration, limited stem cell proliferation and cancer progression.
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Why is it important?
MEIS proteins could be therapeutically targeted to develop therapies for cardiovascular diseases, bone failure, and cancer.
Perspectives
This is a very short review. I hope this article will provide a glimpse into the biology and importance of MEIS proteins as a potential drug targets.
Fatih Kocabas
Yeditepe University
Read the Original
This page is a summary of: Emerging Roles of Meis1 in Cardiac Regeneration, Stem Cells and Cancer, Current Drug Targets, January 2018, Bentham Science Publishers,
DOI: 10.2174/1389450118666170724165514.
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