What is it about?
A patient's response to chemotherapy drugs is often dependent upon how the drug is metabolized by both his or her body and by the tumour itself. This knowledge can be used to uncover effective strategies to improve therapeutic benefit, while minimizing the toxic side effects of the drug.
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Why is it important?
Few research articles focus on chemotherapy drug metabolism by the host and by the tumour and how critical these variables are to the success or failure of treatment.
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This page is a summary of: Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines, Current Drug Metabolism, October 2015, Bentham Science Publishers,
DOI: 10.2174/1389200216888150915112039.
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