What is it about?
We conducted a systematic review and meta-analysis of randomized controlled trials exploring the effect of topical TXA on bleeding cessation in comparison to vasoconstrictors. Our findings clearly lend support to the conclusion that topical TXA has a better effect of improving bleeding cessation and reducing the rebleeding rate than topical vasoconstrictors in otolaryngology-related emergency for epistaxis.
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Why is it important?
Our study provides an alternative treatment option to intuition in the clinical management of epistaxis.
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This page is a summary of: A Systematic Review and Meta-analysis of the Effects of Topical Tranexamic
Acid versus Topical Vasoconstrictors on the Management of Epistaxis, Current Pharmaceutical Design, May 2023, Bentham Science Publishers,
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