What is it about?

Once M. tuberculosis has infected humans, it elaborates strategies for evading the risk to killing by the host immune system and by the anti-tuberculosis agents employed to cure infection. These strategies give rise to a bacterial multi-drug resistance status.

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Why is it important?

Aim of this work was to give an as much as possible comprehensive survey of the literature that might be of interest also to Readers who are not necessarely expert in human tuberculosis.

Perspectives

The clarification of strategies elaborated for surviving by M. tuberculosis has brought to the identification in the last few years of mycobacterial molecular targets worth to exploitation for the development of novel and powerful anti-tuberculosis drugs.

professor giampietro g sgaragli
university of siena

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This page is a summary of: Human Tuberculosis II. M. tuberculosis Mechanisms of Genetic and Phenotypic Resistance to Anti-Tuberculosis Drugs, Current Medicinal Chemistry, May 2016, Bentham Science Publishers,
DOI: 10.2174/0929867323666160405112820.
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