What is it about?

Iron deficiency and iron-related disorders are common health issues worldwide, affecting a significant proportion of the population. Diagnosis and management of these disorders rely heavily on using various iron-related biomarkers that can provide valuable clinical information.

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Why is it important?

This review article provides an overview of the most commonly used iron-related biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor, zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers, such as hepcidin and retinol-binding protein 4, are also discussed.


Iron plays a vital role in various physiological processes, including oxygen transport, energy metabolism, and DNA synthesis. The article highlights the advantages and limitations of iron biomarkers and their clinical applications in diagnosing and managing iron deficiency and iron-related anemia.

habilitated doctor, chemist Monica BUTNARIU
University of Life Sciences "King Mihai I" from Timisoara

Read the Original

This page is a summary of: Iron-related Biomarkers in the Diagnosis and Management of Iron Disorders, Current Medicinal Chemistry, February 2024, Bentham Science Publishers,
DOI: 10.2174/0109298673263003231228060800.
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