What is it about?

Newly synthesized indoles and their derivatives are promising for the treatment of many common diseases, including cancer. The BEI compound was studied for the first time in cancer cell lines and showed a significant anti-cancer effect. Moreover, BEI inhibited a promising glutathione S-transferase (GST) enzyme activity.

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Why is it important?

In this study, BEI, which shows selective cytotoxic activity in cancer cell lines with its GST inhibition activity for the first time, may be a promising new molecule that can be used in the design of anti-cancer drugs.

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This page is a summary of: Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes, Anti-Cancer Agents in Medicinal Chemistry, June 2021, Bentham Science Publishers, DOI: 10.2174/1871520620666200918111940.
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