What is it about?
This study was an up-to-date meta-analysis that focusing on the correlation between ALDH2 polymorphism and LOAD by comprehending five case-control studies. Our results showed that there was no positive significance between ALDH2 polymorphism and LOAD. Whereas, a tendency that the significance became more positive as the sample size enlarged and men with ALDH2*2 had higher risk for LOAD were observed.
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Why is it important?
Our innovation is that this is an up-to-date meta-analysis covering standard case-control studies and scientific analyzing methods. Our conclusion was more acceptable and objective.
Perspectives
Writing this article was a great challenge for me as a first author. This article gave me more confidence in studying Alzheimer's disease to find out likely strategy to postpone the progress of the disease.
Haitao Liu
Fourth Military Medical University
Read the Original
This page is a summary of: Association between ALDH2 Gene Polymorphism and Late-onset Alzheimer Disease: An Up-to-date Meta-analysis, Current Alzheimer Research, April 2020, Bentham Science Publishers,
DOI: 10.2174/1567205017666200317102337.
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