What is it about?
Nematodes, known as eelworms, are an economically harmful group of parasites. The main species that causes damage to plants is Meloidogyne, which causes damage to the roots, making it difficult to absorb water and nutrients necessary for the good development of plants. Bicyclic dicarboxylic acid and bicyclic dialkyl dicarboxylate derivatives were synthesized via Diels-Alder reaction and evaluated against phytonematode Meloidogyne javanica.
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Why is it important?
Nematodes generate a projected annual loss of $ 157 billion worldwide. The effective way to control this pest is through chemical control, but the efficient molecules present in the market have great toxicity to mammals and birds. Thus, there is a constant demand for the development of new nematicide molecules.
Perspectives
The bicyclic dicarboxylic acid was the most active compound compared to the structurally similar ester derivatives. According to the results obtained it is believed that polarity seems to be a key factor for the higher activity of the dicarboxylic acid.
Professor Elson Santiago Alvarenga
Universidade Federal de Vicosa
Read the Original
This page is a summary of: Synthesis and Evaluation of Nematicidal Activity of Compounds Derived from Norbornadiene, Journal of the Brazilian Chemical Society, January 2020, Sociedade Brasileira de Quimica (SBQ),
DOI: 10.21577/0103-5053.20200067.
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