Global and disease-free survival in endometrial cancer: prognostic factors

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This single-center retrospective analysis confirms that FIGO stage and tumor grade are independent prognostic factors of disease-free survival and overall survival in patients diagnosed with endometrial cancer. The preoperative study is critical to define the group of patients who should undergo lymphadenectomy, depending on which is considered high or low risk. As shown, poorly differentiated tumors have a very unfavorable effect on survival and it is necessary to know this information before the patient is in the operating room. Outcome was also influenced by histopathologic tumor type, myometrial and lymphovascular space invasion, lymph-node involvement, age, and tumor remnants after surgery, although a larger study sample is probably needed to demonstrate the independent association of these variables with survival.

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