What is it about?
Inflammation plays a role in the development of cancer. Thus we analyze the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and other clinicopathological determinants in early-stage (cT1/T2N0) tongue cancer
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Why is it important?
Our findings show that Inflammation does play a role in the development of cancer and reflect it in pretreatment lab data, such as neutrophil-to-lymphocyte ratio (NLR). The significant finding is that pretreatment NLR >=2.95 is significantly correlated with a larger tumor, positive neck lymph node metastasis, and positive perineural invasion. Importantly, it indicates reduced survival rate. Therefore, if the NLR >=2.95 in early-stage (cT1/T2N0) tongue cancer is noted preoperatively, it reveals more invasive tumor behavior clinically.
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This page is a summary of: Prognosis of neutrophil-to-lymphocyte ratio in clinical early-stage tongue (cT1/T2N0) cancer, OncoTargets and Therapy, August 2017, Dove Medical Press,
DOI: 10.2147/ott.s140800.
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