What is it about?
In this study, green AuNPs and CuNPs were synthesized via a rapid, simple, inexpensive, and environmentally friendly approach using the fruit extract of SP. The various biomolecules present in the fruit extract of SP were used as reducing, stabilizing, and capping agents for the NPs. The biofabricated NPs were characterized by UV-Vis spectroscopy, FT-IR, TEM, EDX, and Zeta sizer analysis. Antioxidant and anticancer properties of AuNPs and CuNPs synthesized in green media were performed and showed dose-dependent activity. Both Au and Cu NPs showed significant cytotoxicity against MCF-7 and MDA-MB-231 cancer cells. Moreover, both Au and CuNPs have promising antibacterial effects against pathogenic bacterial strains. Green synthesized NPs exhibited enhanced biological activity compared to SP extract.
Featured Image
Photo by fateme Hosseini on Unsplash
Why is it important?
Overall, these green synthesized AuNPs and CuNPs from the fruit extract of SP have the potential for their use in the pharmaceutical and biomedical fields. Despite their excellent performance in improving anticancer and antioxidant activity, further research into the detailed toxicity profiles and metabolic mechanisms of Au and CuNPs is still needed.
Perspectives
These AuNPs and CuNPs are particularly appealing in a variety of applications in the pharmaceutical and medicinal industries due to their economical and environmentally friendly production
Dr Alaaeldin A Hamza
National Organization for Drug Control and Research
Read the Original
This page is a summary of: Biosynthesis and Characterization of Gold and Copper Nanoparticles from Salvadora persica Fruit Extracts and Their Biological Properties, International Journal of Nanomedicine, December 2022, Taylor & Francis,
DOI: 10.2147/ijn.s385543.
You can read the full text:
Contributors
The following have contributed to this page
