What is it about?
We have utilized cells to transport magnetic nanoparticles into pancreatic tumors in a mouse model. A/C Magnetic Hyperthermia treatment was able to prolong the life of the animals by 32%.
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Why is it important?
This is, to be best of our knowledge, the first time that the power of combined cell-delivered nanotherapy and hyperthermia (heat treatment) for treating pancreatic cancer has been demonstrated.
Perspectives
The Troyer and Bossmann groups at Kansas State University are developing cell-mediated therapies for tumors and infectious diseases. The work published here is regarded by the researchers at Kansas State as a breakthrough in delivering nanoparticles in a disseminated pancreatic tumor model in an immunocompetent mouse model.
Stefan Bossmann
Kansas State University
Read the Original
This page is a summary of: Cell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model, International Journal of Nanomedicine, January 2012, Taylor & Francis,
DOI: 10.2147/ijn.s28344.
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