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Blemished skin is the most common skin condition worldwide and commonly affects the face (forehead, cheek, and chin), chest, and back, where sebaceous gland hair follicles are mostly found. In this study, we could show that treatment with the active substance bis-ethylhexyl hydroxydimethoxy benzylmalonate (HDBM; RonaCare® AP) at 2% resulted in a significant reduction of sebum excretion and showed efficacy against inflamed/red lesions also shown by photographic documentation. Efficacy and galenic performance of 2% HDBM were judged to be superior to the placebo emulsion. Additionally, 2% HDBM was well tolerated; approximately 80% of the test subjects rated the compatibility as good to very good.
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This page is a summary of: Sebusuppressive efficacy of the antioxidant bis-ethylhexyl hydroxydimethoxy benzylmalonate in the treatment of oily and blemished skin, Clinical Cosmetic and Investigational Dermatology, August 2012, Taylor & Francis,
DOI: 10.2147/ccid.s32669.
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