Low resolution structure of full-length Rasal, a dual GTPase activating protein

What is it about?

Here we present the low resolution structure of full-length Rasal, obtained by negative staining electron microscopy, which allows us to propose a model of its domain topology. These results help to understand the role of the different domains in controlling the dual GAP activity of GAP1 family proteins.

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Why is it important?

These results help to understand the role of the different domains in controlling the dual GAP activity of GAP1 family proteins.