All Stories

  1. Advancements in Nonviral Gene Editing Strategies for Rare Diseases

    Article • Human Gene Therapy, September 2025, SAGE Publications

    Begoña Sot

  2. CRISPR-associated Plasmonic Colorimeter Method (Ca-PCM): A real-time RGB detection system for gold nanoparticles-based nucleic acid biosensors

    Article • Analytica Chimica Acta, February 2025, Elsevier

    Begoña Sot

  3. Detection of the Uveal Melanoma-Associated Mutation GNAQ Q209P from Liquid Biopsy Using CRISPR/Cas12a Technology

    Article • Analytical Chemistry, November 2023, American Chemical Society (ACS)

    Begoña Sot

  4. Nanomedical research and development in Spain: improving the treatment of diseases from the nanoscale

    Article • Frontiers in Bioengineering and Biotechnology, July 2023, Frontiers

    Begoña Sot

  5. CASCADE: Naked eye-detection of SARS-CoV-2 using Cas13a and gold nanoparticles

    Article • Analytica Chimica Acta, May 2022, Elsevier

    Begoña Sot

  6. Versatile Near‐Infrared Super‐Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD‐2

    Article • Chemistry - A European Journal, March 2022, Wiley

    Begoña Sot

  7. CRISPR/Cas technology as a promising weapon to combat viral infections

    Article • BioEssays, February 2021, Wiley

    Begoña Sot

  8. ARL3 activation requires the co-GEF BART and effector-mediated turnover

    Article • eLife, January 2021, eLife

    Begoña Sot

  9. Assessing the parameters modulating optical losses of iron oxide nanoparticles under near infrared irradiation

    Article • Nanoscale Advances, January 2021, Royal Society of Chemistry

    Begoña Sot

  10. Combining Ag and γ-Fe2O3 properties to produce effective antibacterial nanocomposites

    Article • Colloids and Surfaces B Biointerfaces, October 2020, Elsevier

    Begoña Sot

  11. Role of α-Synuclein Regions in Nucleation and Elongation of Amyloid Fiber Assembly

    Article • ACS Chemical Neuroscience, February 2020, American Chemical Society (ACS)

    Begoña Sot

  12. Long-term STED imaging of amyloid fibers with exchangeable Thioflavin T

    Article • Nanoscale, January 2020, Royal Society of Chemistry

    Begoña Sot

  13. Nanoscale View of Amyloid Photodynamic Damage

    Article • Journal of the American Chemical Society, November 2019, American Chemical Society (ACS)

    Begoña Sot

  14. Self-assembly of repeat proteins: Concepts and design of new interfaces

    Article • Journal of Structural Biology, February 2018, Elsevier

    Begoña Sot

  15. Low resolution structure of full-length Rasal, a dual GTPase activating protein

    Article • Biological Chemistry, December 2017, De Gruyter

    Begoña Sot

  16. eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1

    Article • PLoS Biology, April 2017, PLOS

    Begoña Sot

  17. The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Begoña Sot

  18. Molecular chaperones: functional mechanisms and nanotechnological applications

    Article • Nanotechnology, July 2016, Institute of Physics Publishing

    Begoña Sot

  19. Designed Modular Proteins as Scaffolds To Stabilize Fluorescent Nanoclusters

    Article • Biomacromolecules, November 2015, American Chemical Society (ACS)

    Begoña Sot

  20. Controlled nanometric fibers of self-assembled designed protein scaffolds

    Article • Nanoscale, May 2014, Royal Society of Chemistry

    Begoña Sot

  21. Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes

    Article • Proceedings of the National Academy of Sciences, December 2012, Proceedings of the National Academy of Sciences

    Begoña Sot

  22. Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process

    Article • Journal of Biological Chemistry, January 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Begoña Sot

  23. The Structure of an Arf-ArfGAP Complex Reveals a Ca2+ Regulatory Mechanism

    Article • Cell, December 2010, Elsevier

    Begoña Sot

  24. GTPase activity of Di-Ras proteins is stimulated by Rap1GAP proteins

    Article • Small GTPases, November 2010, Taylor & Francis

    Begoña Sot

  25. The relevance of protein-protein interactions for p53 function: the CPE contribution

    Article • Protein Engineering Design and Selection, October 2010, Oxford University Press (OUP)

    Begoña Sot

  26. The Structure of an Arf-ArfGAP Complex Reveals a Ca2+ Regulatory Mechanism

    Article • Cell, May 2010, Elsevier

    Begoña Sot

  27. Unravelling the mechanism of dual-specificity GAPs

    Article • The EMBO Journal, February 2010, Wiley

    PD Dr. Carsten Kötting, Begoña Sot

  28. Comparative Biophysical Characterization of p53 with the Pro-apoptotic BAK and the Anti-apoptotic BCL-xL

    Article • Journal of Biological Chemistry, August 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Begoña Sot

  29. Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroELE461K

    Article • Journal of Structural Biology, September 2006, Elsevier

    Begoña Sot

  30. Ionic interactions at both inter-ring contact sites of GroEL are involved in transmission of the allosteric signal: A time-resolved infrared difference study

    Article • Protein Science, September 2005, Wiley

    Begoña Sot

  31. GroEL Stability and Function

    Article • Journal of Biological Chemistry, June 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Begoña Sot

  32. Salt Bridges at the Inter-ring Interface Regulate the Thermostat of GroEL

    Article • Journal of Biological Chemistry, July 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Begoña Sot

  33. Excluded Volume Effects on the Refolding and Assembly of an Oligomeric Protein

    Article • Journal of Biological Chemistry, October 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Begoña Sot