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The calculation of the upper limit of normal for cardiac troponin (the test used to detect whether people have had a heart attack) and the number of normals which can be detected, is affected by how carefully the underlying population is checked for the presence or absence of heart disease. We have shown that this reduces the number of women more than the number of men where a normal value can be measured.

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This page is a summary of: Caveat emptor – hidden pitfalls in defining the 99th percentile of cardiac troponin assays, Clinical Chemistry and Laboratory Medicine (CCLM), February 2021, De Gruyter,
DOI: 10.1515/cclm-2021-0067.
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