What is it about?
Microscopic sensors in our ears are needed for normal hearing. We describe how small size changes in parts of these sensors change how they work. These size changes explain measured differences owing to different experimental conditions used to study these sensors.
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Why is it important?
This work implies that size changes of less than 1% in parts of the ear's sensors will cause hearing loss unless additional processes compensate for the size changes.
Perspectives
This paper is an example of how a simple mathematical model can yield important insights into a biological system and make experimentally testable predictions.
Daibhid O Maoileidigh
Stanford University
Read the Original
This page is a summary of: Stereocilium height changes can account for the calcium dependence of the outer-hair-cell bundle’s resting state, PLOS One, May 2025, PLOS,
DOI: 10.1371/journal.pone.0314728.
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