Characterization of heart rate variability in end-stage renal disease patients after kidney transplantation with recurrence quantification analysis

What is it about?

It is known that patients with end-stage renal disease during up active standing have few changes in heart rate variability , which are improved after hemodialysis. However, it is unknown whether the response to active standing is recovered after definitive treatment with kidney transplantation.

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Why is it important?

Heart rate variability (HRV) is a noninvasive approach to studying the autonomic modulation of heart rate in experimental settings, such as active standing sympathetic stimulation. This work aims to assess the change in HRV dynamics in resting position and active standing through time and frequency based metrics, as well as recurrence plot quantitative analysis (RQA). iin kidney transplant recipients. The low-frequency component of HRV and the presence of diagonal and vertical structures in RQA were predominant. A larger estimated glomerular filtration rate was significantly correlated with broader HRV in the supine position and during active standing.

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