What is it about?
This study shows whether a person living with HIV/AIDS having a viral load between 50 to 999 copies/ml is at risk of becoming non-suppressed in Uganda and other African countries with similar settings. This study looked at people living with HIV/AIDS from 2016 to 2020 and compared those with a viral load between 50 to 999 copies/ml and those with a non-detectable viral load, which is below 50 copies/ml in Uganda. It was discovered that people with a viral load between 50 to 999 copies/ml had 4.1 times the risk of becoming non-suppressed, as compared to those with a non-detectable viral load.
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Why is it important?
In many African countries including Uganda, a threshold of 1,000 copies/ml is used to determine viral non-suppression. Hence no intervention is given to people with a viral load between 50 to 999 copies/ml. This study shows the need to reduce the viral load non-suppression threshold from 1,000 copies/ml to 200 copies/ml.
Perspectives
This is a key article for key policy makers in HIV management and control in Sub-Sahara Africa
Nicholus Nanyeenya
Makerere University
Read the Original
This page is a summary of: The association between low-level viraemia and subsequent viral non-suppression among people living with HIV/AIDS on antiretroviral therapy in Uganda, PLOS One, January 2023, PLOS,
DOI: 10.1371/journal.pone.0279479.
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