What is it about?
Molecular modelling of the HCMV IL-10 isoforms
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Why is it important?
The results obtained in this study demonstrate that there is no structural impediment for the formation of complexes between the HCMV IL-10 isoforms with the IL-10R1 receptor and will lead future in vitro analysis of receptor binding.
Perspectives
The knowledge about structure and expression of specific viral IL-10 isoforms has implications for understanding of their properties and role in HCMV immune evasion and pathogenesis
Maria Cristina Carlan da Silva
Universidade Federal do ABC
Read the Original
This page is a summary of: Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor, PLOS One, November 2022, PLOS,
DOI: 10.1371/journal.pone.0277953.
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