What is it about?
Globally, TB is the leading cause of infectious disease morbidity and mortality with many diagnostic uncertainties. Access to affordable and rapid diagnostics remained a major challenge for many developing countries which bear the greatest burden of TB delaying the initiation time to treatment.
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Why is it important?
The proportion of RR-TB we observed in this study was high. A higher proportion of RR TB was detected outside of the RRDR. Neverthless, a significant number of the GeneXpert MTB/RIF Assay probes were identified as unhybridized and this critical observation would mean that most of the probes had no or minimal utility in this geographical region.
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This page is a summary of: High proportion of RR-TB and mutations conferring RR outside of the RRDR of the rpoB gene detected in GeneXpert MTB/RIF assay positive pulmonary tuberculosis cases, in Addis Ababa, Ethiopia, PLoS ONE, December 2022, PLOS, DOI: 10.1371/journal.pone.0277145.
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