What is it about?

This is a systematic review showing the evidences of adverse events associated with the use of histamine-2 antagonists in neonates, with some consequences of its use.

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Why is it important?

The use of such medicines have brought several adverse events, worsening outcomes of neonates with severe to critical conditions at birth and early life.

Perspectives

Most services have stopped using these drugs after these evidences have been highlighted.

Ricardo Gurgel
Universidade Federal de Sergipe

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This page is a summary of: Association between histamine-2 receptor antagonists and adverse outcomes in neonates: A systematic review and meta-analysis, PLoS ONE, April 2019, PLOS,
DOI: 10.1371/journal.pone.0214135.
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