What is it about?
Pediatric siMS score (PsiMS) represents a practical and reliable score for the evaluation of MS in obese youth which is easily calculated and enables continuous metabolic syndrome score assessment and comparison of patients from different populations.
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Why is it important?
The dichotomous nature of the current definition of MS in youth results in loss of information. On the other hand, the calculation of continuous MS scores using standardized residuals in linear regression (Z scores) or factor scores of principal component analysis (PCA) is highly impractical for clinical use. PsiMS score shows high correlation with most of the complex continuous scores (0.792–0.901). PsiMS score represents a practical and accurate score for the evaluation of MS in the obese youth.
Perspectives
The development of PsiMSscore presented in this study should overcome limitations of the IDF MS definition as well as issues of current MS scores in the population of the obese youth, since the PsiMS score has high correlation with previous, more complex scores, while being simple and easy to calculate. Also, PsiMS score is not sample specific, which means that scores from different studies can be compared, as well as changes in score of a single patient. It should be noted that PsiMS score was not developed to replace the complex continuous MS scores, but to serve as a surrogate score with high correlation, similar to HOMA-IR or Matsuda indices in the evaluation of insulin resistance in everyday clinical practice.
Rade Vukovic
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This page is a summary of: Pediatric siMS score: A new, simple and accurate continuous metabolic syndrome score for everyday use in pediatrics, PLoS ONE, December 2017, PLOS,
DOI: 10.1371/journal.pone.0189232.
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