What is it about?
In this study, we demonstrate that a mild brain injury can lead to a delayed loss of inhibitory neurons, reductions in inhibitory synaptic transmission, and increased anxiety-like behavior.
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Why is it important?
This work demonstrates that even after a mild injury, persistent alterations in the amygdala may increase anxiety-like behavior and could be a causal factor for the development of posttraumatic stress disorder.
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This page is a summary of: Reduced GABAergic Inhibition in the Basolateral Amygdala and the Development of Anxiety-Like Behaviors after Mild Traumatic Brain Injury, PLoS ONE, July 2014, PLOS,
DOI: 10.1371/journal.pone.0102627.
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